{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T21:24:17Z","timestamp":1781817857317,"version":"3.54.5"},"reference-count":75,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T00:00:00Z","timestamp":1653091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T00:00:00Z","timestamp":1653091200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1111\/and.14476","type":"journal-article","created":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T06:23:53Z","timestamp":1653200633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Cabbage (\n            <i>Brassica oleracea<\/i>\n            ) mitigates lead (\n            <scp>II<\/scp>\n            ) acetate\u2010induced testicular dysfunction in Wistar rats via up\u2010regulation of Bcl\u20102 protein expression, pituitary\u2013testicular hormonal axis and down\u2010regulation of oxido\u2010inflammatory reactions"],"prefix":"10.1155","volume":"54","author":[{"given":"Tolunigba Abisola","family":"Kolawole","sequence":"first","affiliation":[{"name":"Department of Physiology PAMO University of Medical Sciences  Port\u2010Harcourt Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5600-8288","authenticated-orcid":false,"given":"Jerome Ndudi","family":"Asiwe","sequence":"additional","affiliation":[{"name":"Department of Physiology PAMO University of Medical Sciences  Port\u2010Harcourt Nigeria"},{"name":"Department of Physiology University of Ibadan  Ibadan Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buduchim Rejoice","family":"Buduburisi","sequence":"additional","affiliation":[{"name":"Department of Physiology PAMO University of Medical Sciences  Port\u2010Harcourt Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria Abimbola","family":"Akintade","sequence":"additional","affiliation":[{"name":"Department of Physiology Chrisland University  Abeokuta Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olusegun Gafar","family":"Adebayo","sequence":"additional","affiliation":[{"name":"Department of Physiology PAMO University of Medical Sciences  Port\u2010Harcourt Nigeria"},{"name":"Department of Physiology University of Ibadan  Ibadan Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abodunrin Adebayo","family":"Ojetola","sequence":"additional","affiliation":[{"name":"Department of Physiology Redeemer's University  Ede Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Datonye Victor","family":"Dapper","sequence":"additional","affiliation":[{"name":"Department of Physiology University of Port\u2010Harcourt  Port\u2010Harcourt Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,21]]},"reference":[{"issue":"4","key":"e_1_2_11_2_1","first-page":"366","article-title":"Protective effect of quercetin and or zinc against lead toxicity on rat testes","volume":"9","author":"Abdel\u2010Latief H. M.","year":"2015","journal-title":"Global Journal of Pharmacology"},{"key":"e_1_2_11_3_1","first-page":"7216","article-title":"Protective role of flaxseed oil against lead acetate induced oxidative stress in testes of adult rats","volume":"9","author":"Abdel\u2010Moniem A. E.","year":"2010","journal-title":"African Journal of Biotechnology"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4172\/2161-038X.1000156"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.1517"},{"key":"e_1_2_11_6_1","first-page":"360","article-title":"Some studies on the toxic effects of prolonged lead exposure in male rabbits: Chromosomal and testicular alterations","volume":"8","author":"Ahmed Y. F.","year":"2012","journal-title":"Global Veterinaria"},{"key":"e_1_2_11_7_1","first-page":"30","article-title":"The protective effect of flaxseed oil supplemented with high source of branched chain amino acids against the rat's testicular toxicity induced by lead acetate, world","volume":"6","author":"Ahmed\u2010Farid O. A.","year":"2017","journal-title":"Journal of Pharmacy & Pharmaceutical Sciences"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.15835\/nsb549125"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.05.059"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.12817"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2014.03.009"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-015-0851-9"},{"key":"e_1_2_11_13_1","first-page":"387","article-title":"Protective effect of chufa tubers (Cyperus esculentus) on induction of sperm abnormalities in mice treated with lead acetate","volume":"5","author":"Al\u2010Shaikh M. N.","year":"2013","journal-title":"International Journal of Drug Development and Research"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.21123\/bsj.7.1.389-393"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12303"},{"key":"e_1_2_11_16_1","first-page":"158","article-title":"Pharmacology of free radicals and the impact of reactive oxygen species on the testis","volume":"14","author":"Aprioku J. S.","year":"2013","journal-title":"Journal of Reproduction and Infertility"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573407216666200127130014"},{"issue":"4","key":"e_1_2_11_18_1","first-page":"201","article-title":"The effect of high dietary salt consumption on renal function in Streptozotocin\u2010induced diabetic male Wistar rats","volume":"6","author":"Asiwe J. N.","year":"2021","journal-title":"International Journal of Nutritional Sciences"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/1354750X.2021.2022210"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00580-010-0964-y"},{"key":"e_1_2_11_21_1","first-page":"190","article-title":"Protective effect of ethyl pyruvate on epididymal sperm characteristics, oxidative stress and testosterone level in methotrexate\u2010treated mice","volume":"14","author":"Atashfaraz E.","year":"2013","journal-title":"Journal of Reproduction and Infertility"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.7917"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.796"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)50881-X"},{"key":"e_1_2_11_25_1","first-page":"43","article-title":"Effects of lead on gonadal activity in albino rats, Kathmandu Univ","volume":"2","author":"Biswas N. M.","year":"2004","journal-title":"Medizinhistorisches Journal"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/69.1.149"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12291-011-0122-6"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.3923\/ajbkr.2015.39.45"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2014.10.010"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-017-0750-3"},{"key":"e_1_2_11_31_1","first-page":"2209","article-title":"Protective effect of aquilegia vulgaris (L) against lead acetate\u2010induced oxidative stress in rats, food Chem","volume":"47","author":"El\u2010Nekeety A. A.","year":"2009","journal-title":"Toxicology"},{"issue":"1","key":"e_1_2_11_32_1","first-page":"26","article-title":"The curcumin as antioxidant natural herb, with emphasize on its effects against some disease","volume":"7","author":"Elsayed A. S. I.","year":"2016","journal-title":"International Journal of Applied Biology and Pharmaceutical Technology"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2007.00005.x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1076\/apab.109.5.457.8035"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/c1np00051a"},{"key":"e_1_2_11_36_1","first-page":"2000","volume-title":"Textbook of medical physiology","author":"Guyton A. C.","year":"2000"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.01.007"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.01.072"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(97)00090-5"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/29.4.6166661"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/130261"},{"key":"e_1_2_11_42_1","first-page":"125","article-title":"The protective effect of vitamic C on azathioprine induced semiferous tubules structural changes and cytogenetic toxicity in albino rats","volume":"4","author":"Karawya F. J.","year":"2006","journal-title":"Cancer Therapy"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.2174\/157488608783333907"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.9734\/jamps\/2020\/v22i1230208"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S154608"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(95)03107-Q"},{"key":"e_1_2_11_47_1","first-page":"1991","article-title":"Overexpression of manganese\u2010containing superoxide dismutase confers resistance to the cytotoxicity of tumor necrosis factor alpha and\/or hyperthermia","volume":"57","author":"Li J. J.","year":"1997","journal-title":"Cancer Research"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1810493"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0272-0590(91)90127-P"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)63504-5"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod51.5.945"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2008.01.019"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221-1691(11)60187-1"},{"key":"e_1_2_11_54_1","first-page":"153","article-title":"Structural alteration of spermatozoa in the persons employed in lead acid battery factory","volume":"49","author":"Naha N.","year":"2005","journal-title":"Indian Journal of Physiology and Pharmacology"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.66032.x"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.13780"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.9790\/0853-13199297"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(79)90738-3"},{"key":"e_1_2_11_59_1","first-page":"114","article-title":"Lead toxicity part II: The role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity","volume":"11","author":"Patrick L.","year":"2006","journal-title":"Alternative Medicine Review"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.3.816-834.2002"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01688309"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2006000300003"},{"key":"e_1_2_11_63_1","first-page":"115","article-title":"Studies on the reproductive activities of Ricinus communis seed in male albino rats, Asian","volume":"8","author":"Raji Y.","year":"2006","journal-title":"Journal of Andrology"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1515\/REVEH.2009.24.1.15"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1994.tb01077.x"},{"key":"e_1_2_11_66_1","first-page":"134","article-title":"Endocrine disruptors and estrogenic effects on male reproductive axis, Asian","volume":"10","author":"Sikka S. C.","year":"2008","journal-title":"Journal of Andrology"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-015-0280-0"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.4103\/1735-5362.213983"},{"issue":"10","key":"e_1_2_11_69_1","first-page":"32","article-title":"Mechanisms of endothelial cell protection by curcumin in hypercholesterolemia","volume":"1","author":"Sudjarwo S. A.","year":"2011","journal-title":"Journal of Applied Pharmaceutical Science"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110491"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2007.04644.x"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.2307\/1590170"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1080\/009841099157953"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(83)90051-6"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1110(83)90014-3"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-6915(02)00168-0"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.14476","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/and.14476","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.14476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:40:12Z","timestamp":1671540012000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.14476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,21]]},"references-count":75,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/and.14476"],"URL":"https:\/\/doi.org\/10.1111\/and.14476","archive":["Portico"],"relation":{},"ISSN":["0303-4569","1439-0272"],"issn-type":[{"value":"0303-4569","type":"print"},{"value":"1439-0272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,21]]},"assertion":[{"value":"2022-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}