{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:47:22Z","timestamp":1791316042275,"version":"4.3.1"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,18]],"date-time":"2015-09-18T00:00:00Z","timestamp":1442534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>This study sought to investigate whether isolated abnormal strict morphology (&lt;5% normal forms) and very low strict morphology (0\u20131% normal forms) affects pregnancy rates in intrauterine insemination (IUI). This was a retrospective study performed at an Academic Medical Center\/Reproductive Medicine Center. Four hundred and eight couples were included for 856 <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> cycles. 70 <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> cycles were performed in couples with abnormal strict morphology and otherwise normal semen parameters. Outcomes were measured as clinical pregnancy rate per <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> cycle as documented by fetal heart activity on maternal ultrasound. Clinical pregnancy rate did not significantly differ between the group with abnormal strict morphology [11\/70 (15.7%)] and the normal morphology group [39\/281 (13.9%)]. Additionally, there was no significant difference between the pregnancy rate in the abnormal morphology group compared to that of our overall institutional <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> pregnancy rate [145\/856 (16.9%)]. Furthermore, there was no significant difference between pregnancy rate in the very low morphology group [3\/14 (21.4%)] compared to those with normal morphology or the overall <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> pregnancy rate. Patients with isolated abnormal strict morphology have clinical pregnancy rates similar to those with normal morphology for <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content>. Even in those with very low normal forms, consideration of <jats:styled-content style=\"fixed-case\">IUI<\/jats:styled-content> for assisted reproduction should not be excluded.<\/jats:p>","DOI":"10.1111\/andr.12098","type":"journal-article","created":{"date-parts":[[2015,9,19]],"date-time":"2015-09-19T00:50:11Z","timestamp":1442623811000},"page":"1088-1093","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Isolated abnormal strict morphology is not a contraindication for intrauterine insemination"],"prefix":"10.1111","volume":"3","author":[{"given":"G. M.","family":"Lockwood","sequence":"first","affiliation":[{"name":"Department of Urology Froedtert Hospital Medical College of Wisconsin Affiliated Hospitals Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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