{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T12:03:27Z","timestamp":1781870607293,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,5,6]],"date-time":"2016-05-06T00:00:00Z","timestamp":1462492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI13\/01237"],"award-info":[{"award-number":["PI13\/01237"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007801","name":"Fundaci\u00f3n S\u00e9neca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The distance from the genitals to the anus, anogenital distance, reflects androgen concentration during prenatal development in mammals. The use of anogenital distance in human studies is still very limited and the quality and consistency of measurements is an important methodological issue. The aim of this study was to assess the feasibility and reproducibility of adult male anogenital distance measurements by two different methods. All men were attending an outpatient clinic at a university hospital and underwent an andrological examination and completed a brief questionnaire. Two variants of anogenital distance [from the anus to the posterior base of the scrotum (<jats:styled-content style=\"fixed-case\">AGD<jats:sub>AS<\/jats:sub><\/jats:styled-content>) and to the cephalad insertion of the penis (<jats:styled-content style=\"fixed-case\">AGD<jats:sub>AP<\/jats:sub><\/jats:styled-content>)] by two methods (lithotomy or frog\u2010legged position) were assessed in 70 men. Within and between coefficient of variations, intra\u2010class correlation coefficients, two\u2010way repeated\u2010measures analysis of variance, and scatter and Bland\u2013Altman plots were calculated. The two methods produced similar values for <jats:styled-content style=\"fixed-case\">AGD<jats:sub>AP<\/jats:sub><\/jats:styled-content> but different estimates for <jats:styled-content style=\"fixed-case\">AGD<jats:sub>AS<\/jats:sub><\/jats:styled-content>. Nonetheless, the overall agreement (<jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content>\u00a0\u2265\u00a00.80) was acceptable for both measures. Therefore, both methods are internally consistent and adequate for epidemiological studies, and may be used depending on the available medical resources, clinical setting, and populations.<\/jats:p>","DOI":"10.1111\/andr.12202","type":"journal-article","created":{"date-parts":[[2016,5,6]],"date-time":"2016-05-06T17:57:42Z","timestamp":1462557462000},"page":"626-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparability and reproducibility of adult male anogenital distance measurements for two different methods"],"prefix":"10.1111","volume":"4","author":[{"given":"J.","family":"Mendiola","sequence":"first","affiliation":[{"name":"Division of Preventive Medicine and Public Health Department of Health and Social Sciences University of Murcia School of Medicine Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"O\u00f1ate\u2010Celdr\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Samper\u2010Mateo","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. J.","family":"Arense\u2010Gonzalo","sequence":"additional","affiliation":[{"name":"Division of Preventive Medicine and Public Health Department of Health and Social Sciences University of Murcia School of Medicine Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Torres\u2010Roca","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"S\u00e1nchez\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Garc\u00eda\u2010Escudero","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. O.","family":"Fontana\u2010Compiano","sequence":"additional","affiliation":[{"name":"Department of Urology \u2018Reina Sofia\u2019 University General Hospital Murcia (Murcia) Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. L.","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Department of Urology and Obstetrics\/Gynecology Stanford University School of Medicine Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. H.","family":"Swan","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Icahn School of Medicine at Mount Sinai New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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