{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T17:26:39Z","timestamp":1773768399607,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T00:00:00Z","timestamp":1477612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Although vitamin D deficiency is one of the most common health problems throughout the world, including Iran, conflicting information exists on the potential association between serum vitamin D levels and semen quality. This study intended to evaluate the association between serum vitamin D [25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>) D3] with semen quality and hormones in Iranian subfertile men. We also compared mean vitamin D and hormone levels in normospermic men with oligoasthenoteratozoospermia (<jats:styled-content style=\"fixed-case\">OAT<\/jats:styled-content>) men. This cross\u2010sectional study was conducted on 278 men who were referred to Royan Infertility Clinic (Tehran, Iran) from March to September 2014. The participants were categorized into two groups; of 186 normospermic and 92 <jats:styled-content style=\"fixed-case\">OAT<\/jats:styled-content> patients according to World Health Organization 2010 criteria. Each participant provided informed consent prior to launching research. Participants completed two general questionnaires of nutritional status. Blood and semen samples were obtained for assessment, and all data were adjusted for age, body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>), and season. Vitamin D levels were classified according to Institute of Medicine guidelines. Vitamin D deficiency, insufficiency, and normal levels were observed in 8.6%, 43.6%, 47.8% of participants, respectively. No association was found between daily dietary intake of vitamin D and calcium with sperm parameters. Serum vitamin D was inversely correlated with <jats:styled-content style=\"fixed-case\">PTH<\/jats:styled-content> (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.045). In normospermic men, serum vitamin D levels categorized were not correlated with semen parameters and reproductive hormones (<jats:styled-content style=\"fixed-case\">FSH<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> LH<\/jats:styled-content>, testosterone(T), and <jats:styled-content style=\"fixed-case\">FT<\/jats:styled-content>), whereas sperm motility showed a positive correlation with vitamin D categorized in <jats:styled-content style=\"fixed-case\">OAT<\/jats:styled-content> men (<jats:italic>rs<\/jats:italic>\u00a0=\u00a00.131, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.028). In conclusion, there was a high incidence of deficiency and insufficiency 25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>) D Levels (&lt;20ng\/ml) observed in Iranian men (52.2%). Moreover, our findings showed a correlation between vitamin D levels and sperm motility in <jats:styled-content style=\"fixed-case\">OAT<\/jats:styled-content> men, which requires further studies.<\/jats:p>","DOI":"10.1111\/andr.12280","type":"journal-article","created":{"date-parts":[[2016,10,28]],"date-time":"2016-10-28T17:12:44Z","timestamp":1477674764000},"page":"113-118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Association of vitamin D status with semen quality and reproductive hormones in Iranian subfertile men"],"prefix":"10.1111","volume":"5","author":[{"given":"Sh.","family":"Abbasihormozi","sequence":"first","affiliation":[{"name":"Department of Embryology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kouhkan","sequence":"additional","affiliation":[{"name":"Department of Embryology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.R.","family":"Alizadeh","sequence":"additional","affiliation":[{"name":"Department of Animal Science Saveh Branch Islamic Azad University Saveh Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.H.","family":"Shahverdi","sequence":"additional","affiliation":[{"name":"Department of Embryology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.H.","family":"Nasr\u2010Esfahani","sequence":"additional","affiliation":[{"name":"Department of Reproductive Biotechnology Reproductive Biomedicine Research Center Royan Institute for Biotechnology ACECR Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.","family":"Sadighi Gilani","sequence":"additional","affiliation":[{"name":"Department of Andrology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"},{"name":"Department of Urology School of Medicine Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Salman Yazdi","sequence":"additional","affiliation":[{"name":"Department of Andrology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Matinibehzad","sequence":"additional","affiliation":[{"name":"Department of Embryology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Zolfaghari","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Female Infertility Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,10,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2011.07.006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-8-91"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-7-140"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02872388"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)56953-2"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2013.262"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2012.02.020"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq024"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der059"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/M13-1788"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn055"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-011-0071-2"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-013-2959-9"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2000.00595.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2012.77"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0385"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-10-519"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2005.00635.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(83)91095-1"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0743"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-2450"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2008.11.015"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980009991698"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.009"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2005.02363.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-1409"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.05.019"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/841615"},{"key":"e_1_2_6_30_1","first-page":"45","article-title":"Vitamin d deficiency in healthy male population: results of the Iranian multi\u2010 center osteoporosis study","volume":"39","author":"Rahnavard Z","year":"2010","journal-title":"Iran J Public Health"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.11.002"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2218"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des280"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.10.008"},{"key":"e_1_2_6_35_1","unstructured":"Scientific IoMUSCot. (1997)Evaluation of Dietary Reference Intakes. N01 OD042139\/NIH HHS\/United States."},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.142137"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/122.6.1338"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2009.03777.x"},{"key":"e_1_2_6_39_1","volume-title":"WHO Laboratory Manual for the Examination and Processing of Human Semen","author":"World Health Organization (WHO)","year":"2010"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.285"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2012.01287.x"}],"container-title":["Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fandr.12280","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fandr.12280","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/andr.12280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T09:43:42Z","timestamp":1694943822000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/andr.12280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,28]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/andr.12280"],"URL":"https:\/\/doi.org\/10.1111\/andr.12280","archive":["Portico"],"relation":{},"ISSN":["2047-2919","2047-2927"],"issn-type":[{"value":"2047-2919","type":"print"},{"value":"2047-2927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,28]]},"assertion":[{"value":"2016-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}