{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T03:00:23Z","timestamp":1769914823906,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Andrologists, cardiologists and diabetologists (and general practitioners) have the great opportunity to collaborate and find shared clinical workup for the benefit of a large number of men. Several evidence established a link between erectile dysfunction (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>), cardiovascular disease (<jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>), diabetes, and metabolic syndrome. Not only these conditions share many risk factors and pathophysiological mechanisms but also an emerging paradigm indicates that <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> is, in fact, an independent marker of cardiovascular disease risk, <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> events and <jats:styled-content style=\"fixed-case\">CV<\/jats:styled-content> mortality. However, there is no consensus on the best cardiologic investigation in men with <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> with no known <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> and, on the contrary, on what is the clinical and prognostic role of detecting <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> during cardiovascular investigation and <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> risk assessment. Only vasculogenic <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>, which represents the most common type of organic <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>, indeed represents a harbinger of <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>, especially for younger patients, and might be diagnosed by dynamic penile color doppler ultrasonography, which represents a real cardiovascular imaging technique that give evidence on the presence of systemic endothelial dysfunction and atherosclerosis. Furthermore, assessment of glucose and lipid metabolism is warranted as first step workup in all <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> patients, and diabetologists should ask their patients for erectile function, address <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> patients to andrologists, and consider vasculogenic <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> in the context of the cardiovascular and metabolic workup and in the context of diabetic complications. Sexual symptoms (and testosterone levels) should sound as harbinger for cardiovascular and metabolic investigation and cardiologists and diabetologists have the opportunity to have a symptom (erectile dysfunction) and a vascular test (penile color doppler) that help them in better management of patients, their comorbidities and complications.<\/jats:p>","DOI":"10.1111\/andr.12342","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T20:46:42Z","timestamp":1488919602000},"page":"408-413","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["The great opportunity of the andrological patient: cardiovascular and metabolic risk assessment and prevention"],"prefix":"10.1111","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6576-2183","authenticated-orcid":false,"given":"C.","family":"Foresta","sequence":"first","affiliation":[{"name":"Department of Medicine Unit of Andrology and Reproductive Medicine University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ferlin","sequence":"additional","affiliation":[{"name":"Department of Medicine Unit of Andrology and Reproductive Medicine University of Padova Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Lenzi","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine Section\u00a0of Medical Pathophysiology, Food and Science and Endocrinology Sapienza University of Rome Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Montorsi","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences and Community Health Centro Cardiologico Monzino IRCCS University of Milan Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Italian Study Group on Cardiometabolic Andrology","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.13084"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000485"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2354"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2008.01112.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2010.01117.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0447"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2015.11.003"},{"key":"e_1_2_10_9_1","unstructured":"DohleGR ArverS BettocchiC JonesTH KlieschS&PunabM. 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