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There is also evidence that the disease is linked to other reproductive issues in men\u2014specifically delayed puberty, low testosterone, and sperm abnormalities\u2014although the causes of these problems are less clear. Treatment of sickle cell anemia can have effects on the reproductive system as well. This review summarizes the findings from various publications pertaining to reproductive endocrinology, along with their conclusions and discrepancies.<\/jats:p>","DOI":"10.1111\/andr.12370","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T21:16:35Z","timestamp":1498770995000},"page":"679-690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Reproductive endocrine issues in men with sickle cell anemia"],"prefix":"10.1111","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0846-5796","authenticated-orcid":false,"given":"A. 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