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Evidence in the literature indicates that impaired reproductive capacity in wildlife and laboratory species is associated with chemical exposures. In particular, bisphenol A (BPA) and di (2\u2010ethylhexyl) phthalate (DEHP) have generated public interest due to their presence in several consumer products. In this study, we determined that expression of steroid hormone receptors (estrogen and androgen receptors), Wnt4, and \u03b2\u2010catenin was greater (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) in the rat epididymis at 35\u00a0days of age compared to 21 and 90\u00a0days. Second, timed\u2010pregnant Long\u2010Evans dams were exposed to the chemicals <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DEHP<\/jats:styled-content> by gavage from gestational days 12\u201321. The caput epididymis was collected from cohorts of male offspring at 35 and 90\u00a0days of age and processed for Western blot analysis. Results showed that prenatal <jats:styled-content style=\"fixed-case\">BPA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DEHP<\/jats:styled-content> exposures affected (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05) expression of estrogen and androgen receptor, Wnt4, \u03b2\u2010catenin, <jats:styled-content style=\"fixed-case\">MAPK<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">HOXD<\/jats:styled-content>4 protein in the epididymis. Data have implications for morphological development of the epididymis, a possibility that would be explored in future studies.<\/jats:p>","DOI":"10.1111\/andr.12451","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T01:05:23Z","timestamp":1514336723000},"page":"214-222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exposures of male rats to environmental chemicals [bisphenol A and di (2\u2010ethylhexyl) phthalate] affected expression of several proteins in the developing epididymis"],"prefix":"10.1111","volume":"6","author":[{"given":"F. 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