{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:09:56Z","timestamp":1790827796333,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T00:00:00Z","timestamp":1559779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Limited studies have explored the association between gaseous pollutant exposures and male reproductive outcomes, and findings remained inconsistent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To\u00a0evaluate the potential association \u00a0between\u00a0gaseous pollutants\u00a0and semen quality within different exposure windows.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and\u00a0Methods<\/jats:title><jats:p>We adopted semen quality data of 1852 subjects who attended the Reproductive Medicine Center of Renmin Hospital at Wuhan University during January 1st, 2013, to August 3rd, 2015. A generalized linear model was employed to assess the relationship between each exposure variable and sperm parameters in different exposure windows.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> exposure with lag\u00a00\u201390\u00a0days was significantly associated with decreased sperm concentration (\u03b2: \u22121.362; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22121.844, \u22120.879), sperm count (\u03b2: \u22122.979; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22124.267, \u22121.691), and <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> (\u03b2: \u22120.551; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22120.710, \u22120.393). Similar trends were observed for <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> exposure with three other key periods (lag 0\u20139, 10\u201314, and 70\u201390\u00a0days). <jats:styled-content style=\"fixed-case\">NO<\/jats:styled-content><jats:sub>2<\/jats:sub> exposure with lag\u00a00\u201390\u00a0days was also associated with decreased sperm concentration (\u03b2: \u22120.517; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22121.006, \u22120.027), sperm count (\u03b2: \u22121.914; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22123.214, \u22120.615), and <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> (\u03b2: \u22120.264; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u22120.425, \u22120.102). No relationship between gaseous pollutant exposure and ejaculate volume was observed in any exposure window.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusion<\/jats:title><jats:p>Our study indicated a strong adverse effect of gaseous pollutants on semen quality outcomes during the sperm development. Gaseous pollution exposure appeared to be more detrimental in the initial phase of spermatogenesis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.12655","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T09:25:25Z","timestamp":1559813125000},"page":"117-124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Gaseous pollutant exposure affects semen quality in central China: a cross\u2010sectional study"],"prefix":"10.1111","volume":"8","author":[{"given":"X.","family":"Wang","sequence":"first","affiliation":[{"name":"Reproductive Medicine Center Renmin Hospital of Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management School of Health Sciences Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1659-8444","authenticated-orcid":false,"given":"B.","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management School of Health Sciences Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center Renmin Hospital of Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Li","sequence":"additional","affiliation":[{"name":"Centre for Diseases Control and Prevention of the Lianyungang Economic and Technological Development Area Lianyungang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Public Health Wuhan University of Science and Technology School of Medicine Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management School of Health Sciences Wuhan University Wuhan China"},{"name":"Global Health Institute Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center Renmin Hospital of Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management School of Health Sciences Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Yang","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Center Renmin Hospital of Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Healthcare Management School of Health Sciences Wuhan University Wuhan China"},{"name":"Global Health Institute Wuhan University Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1210031"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346481"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6854.609"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001120103"},{"key":"e_1_2_8_6_1","first-page":"9","article-title":"Who laboratory manual for the examination and processing of human semen","volume":"30","author":"Cooper T","year":"2009","journal-title":"J Androl"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2015.10.044"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2011.173"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2015.06.010"},{"key":"e_1_2_8_10_1","first-page":"372","article-title":"Is The Quality of Donated Semen Deteriorating? 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