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Furthermore, codeine caused a marked rise in penile reflexes evident by a significant increase in erections, quick flips, long flips and total penile reflexes. However, copulatory efficiency and fertility index were significantly lower in codeine\u2010treated groups when compared with the control. Serum levels of testosterone were also significantly lower in the treated groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study demonstrates that codeine\u2010induced enhancement of sexual performance is via a testosterone\u2010independent mechanism. It also reveals that although codeine enhances copulatory locomotor activity, it is a potential risk factor for infertility.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.12717","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T22:18:56Z","timestamp":1571437136000},"page":"509-515","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Assessment of sexual behaviour and fertility indices in male rabbits following chronic codeine use"],"prefix":"10.1111","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0992-1653","authenticated-orcid":false,"given":"A. F.","family":"Ajayi","sequence":"first","affiliation":[{"name":"Department of Physiology College of Medicine Ladoke Akintola University of Technology Ogbomoso Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3874-5927","authenticated-orcid":false,"given":"R. 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