{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:41:03Z","timestamp":1788349263800,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although few studies have reported fertility outcomes, no study has reported risk factors that might predict sperm retrieval and pregnancy in azoospermic men with a history of cryptorchidism in a large series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate fertility outcomes and predictors for successful sperm retrieval and pregnancy in azoospermic men with a history of cryptorchidism who underwent microdissection testicular sperm extraction (mTESE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This retrospective observational study included 327 azoospermic men with a history of cryptorchidism who underwent mTESE. Fertility outcomes including sperm retrieval, fertilization rate, number of transferred embryos, pregnancy, miscarriage, and live birth rates were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sperm retrieval was observed in 172 (52.6%) of the patients. The mean fertilization, pregnancy, and live birth rates were 55.2%\u00b120.5, 53.5%, and 44.8%, respectively. The sperm retrieval rate was significantly higher at the orchidopexy age of\u00a0\u2264\u00a09.5\u00a0years (70.8%) than the orchidopexy age of\u00a0&gt;\u00a09.5\u00a0years (42.1%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). Patients with total testicular volume of\u00a0\u2265\u00a013.75\u00a0mL had significantly higher sperm retrieval rate (65.2%) than the patients with total testicular volume of\u00a0&lt;\u00a013.75\u00a0mL (45.5%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.001). Patients with total testosterone level of\u00a0\u2265\u00a0300.5\u00a0ng\/dL had significantly higher sperm retrieval rate (65.6%) than the patients with total testosterone level of\u00a0&lt;\u00a0300.5\u00a0ng\/dL (40.3%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). Patients with follicle\u2010stimulating hormone (FSH) level of\u00a0\u2264\u00a017.25 mIU\/ml had significantly higher sperm retrieval rate (72.3%) than the patients with FSH level of\u00a0&gt;\u00a017.25 mIU\/mL (44.4%) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). Younger male and female ages, and higher fertilization rates were the parameters that might predict pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Infertile azoospermic men with a history of cryptorchidism have high sperm retrieval rate with mTESE. Patients who had orchidopexy at the age of\u00a0\u2264\u00a09.5\u00a0years, and having total testicular volumes of\u00a0\u2265\u00a013.75\u00a0mL with total testosterone level of\u00a0&gt;\u00a0300.5\u00a0ng\/dL and FSH level of\u00a0\u2264\u00a017.25 mIU\/mL have higher success rate for sperm retrieval.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.12910","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T14:35:30Z","timestamp":1600785330000},"page":"253-259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Fertility outcomes and predictors for successful sperm retrieval and pregnancy in 327 azoospermic men with a history of cryptorchidism who underwent microdissection testicular sperm extraction"],"prefix":"10.1111","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4784-2208","authenticated-orcid":false,"given":"Selahittin","family":"\u00c7ayan","sequence":"first","affiliation":[{"name":"Department of Urology University of Mersin School of Medicine Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130rfan","family":"Orhan","sequence":"additional","affiliation":[{"name":"F\u0131rat University School of Medicine Elaz\u0131\u011f Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar\u0131\u015f","family":"Altay","sequence":"additional","affiliation":[{"name":"Ege University School of Medicine \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"A\u015fc\u0131","sequence":"additional","affiliation":[{"name":"Ondokuz May\u0131s University School of Medicine Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"Akbay","sequence":"additional","affiliation":[{"name":"Department of Urology University of Mersin School of Medicine Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Ayas","sequence":"additional","affiliation":[{"name":"Ondokuz May\u0131s University School of Medicine Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6nder","family":"Yaman","sequence":"additional","affiliation":[{"name":"Ankara University School of Medicine Ankara 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