{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T18:47:33Z","timestamp":1789670853413,"version":"4.0.1"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and progression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To explore the relationship between degree of sexual maturation and anthropometric measures in Norwegian boys.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The following endpoints were collected in a Norwegian cross\u2010sectional study of 324 healthy boys aged 9\u201316: ultrasound\u2010determined testicular volume (USTV), total serum testosterone, Tanner pubic hair stage, height, weight, waist circumference (WC), subscapular skinfolds (SSF), and body fat percentage (%BF). Testicular volume\u2010for\u2010age <jats:italic>z<\/jats:italic>\u2010scores were used to classify \u201cearly,\u201d \u201caverage,\u201d or \u201clate\u201d maturing boys. Ordinal logistic regression analyses with a proportional odds model were applied to analyze the association between anthropometric variables and age\u2010adjusted degree of pubertal development, with results expressed as age\u2010adjusted odds ratios (AOR). Cumulative incidence curves for reaching pubertal milestones were stratified by BMI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Boys with a low BMI for age (BMI<jats:italic><jats:sub>z<\/jats:sub><\/jats:italic>\u00a0&lt;\u00a0\u22121) were less likely to have reached a pubertal testicular volume (USTV\u00a0\u2265\u00a02.7\u00a0mL) or a pubertal serum level of testosterone (\u22650.5\u00a0nmol\/L) compared to normal weight boys (AOR 0.3, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.038, AOR 0.3, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.026, respectively), and entered puberty on average with a delay of approximately eight months. Boys with high BMI for age (BMI<jats:italic><jats:sub>z<\/jats:sub><\/jats:italic>\u00a0&gt;\u00a01) exhibited a comparable timing as normal weight boys. The same was found for WC. Pubertal markers were not associated with SSF or %BF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>By examining the association between puberty and weight status classified as low, average, or high, we found that a low BMI or WC for age were associated with a less advanced pubertal development and delayed timing of puberty in boys. No significant association was observed for a high BMI or WC. Moreover, no significant effects of SSF or %BF were observed. A low weight status should also be considered when assessing pubertal development in boys.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.12985","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T10:06:25Z","timestamp":1612605985000},"page":"837-845","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Low BMI, but not high BMI, influences the timing of puberty in boys"],"prefix":"10.1111","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0610-9571","authenticated-orcid":false,"given":"Ninnie Helen Bakken","family":"Oehme","sequence":"first","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Roelants","sequence":"additional","affiliation":[{"name":"Environment and Health Department of Public Health and Primary Care KU Leuven \u2013 University of Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingvild S\u00e6rvold","family":"Bruserud","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Madsen","sequence":"additional","affiliation":[{"name":"Department of Medical Biochemistry and Pharmacology Hormone Laboratory Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Bjerknes","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Rosendahl","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital of North Norway Troms\u00f8 Norway"},{"name":"Department of Clinical Medicine University of Troms\u00f8 The Arctic University of Norway Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petur B.","family":"Juliusson","sequence":"additional","affiliation":[{"name":"Department of Clinical Science University of Bergen Bergen Norway"},{"name":"Department of Pediatrics Haukeland University Hospital Bergen Norway"},{"name":"Department of Health Registry Research and Development Norwegian Institute of Public Health Oslo 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