{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T23:01:09Z","timestamp":1788908469328,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Male circumcision is a well\u2010known old surgery, and several recently developed techniques have been scaled up, including the introduction of laser technology, as alternative approaches to overcome morbidity of conventional surgery scalpel\/suture method<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to perform a systematic review and meta\u2010analysis of studies comparing laser circumcision versus conventional circumcision technique in terms of perioperative outcomes and efficacy (complications, unacceptable appearance, reoperation rate) both in children and adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>This review was performed following the 2020 Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses framework. Continuous variables were analyzed using the inverse variance of the mean difference with a random effect, 95% confidence interval (CI), and <jats:italic>p<\/jats:italic>\u2010value. The incidence of complications, unacceptable appearance, and reoperation rate were pooled using the Cochran\u2010Mantel\u2010Haenszel Method with the random effect model and reported as odds ratio (OR), 95% CI, and <jats:italic>p<\/jats:italic>\u2010value. Significance was set at <jats:italic>p<\/jats:italic>\u2010value \u22640.05 and 95%CI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven studies were included. In comparison to the conventional circumcision, laser circumcision shoved lower visual analogue score at 24\u2010h, and 7 days after surgery, a lower rate of overall complication rate (OR 0.33, 95% CI 0.24\u20130.47, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), scarring (OR 0.09, 95% CI 0.02, 0.41, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002), and unacceptable appearance (OR 0.09, 95% CI 0.05, 0.15, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). We found no statistically significant difference in surgical time, and incidence of bleeding, infection, wound dehiscence, and reoperation rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and conclusion<\/jats:title><jats:p>Our review infers that laser\u2010assisted circumcision is certainly a safe and strong contender as the procedure of choice in both children and adult populations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.13321","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T17:54:05Z","timestamp":1666029245000},"page":"54-64","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Does using a laser improve outcomes of conventional circumcision in adult and children populations? 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