{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T23:55:58Z","timestamp":1775174158468,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T00:00:00Z","timestamp":1685664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cryptorchidism is considered to be one of the most common causes of non\u2010obstructive azoospermia. There are several surgical techniques to retrieve sperm in these patients. Microdissection testicular sperm extraction (m\u2010TESE) is a recent sperm retrieval technique which is considered to be a safe, non\u2010blind, and feasible method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to investigate sperm retrieval rate (SRR) by the mTESE method in patients who have undergone orchidopexy due to bilateral cryptorchidism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>In this retrospective study, 56 ex\u2010cryptorchid patients, who underwent mTESE due to post orchidopexy azoospermia, were included. Patients with hypogonadotropic hypogonadism, Klinefelter syndrome, azoospermia factors (AZF) microdeletion, or chromosomal translocation were excluded from the study. Data were obtained from medical files.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>SRR in this study was 46%. Patients were divided into two groups of negative (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) and positive (<jats:italic>n<\/jats:italic>\u00a0=\u00a026) based on the sperm extraction outcomes. There was no statistically significant difference between two groups regarding the mean age at mTESE, mean age at orchidopexy, testicular size, and serum testosterone concentration. However, testicular location, histological patterns, FSH, and LH level showed to have statistically significant relation with sperm retrieval results. But, according to our logistic regression, none of the included variable in the model including FSH, LH, histopathology, and testis location have a significant effect on the presence of the sperm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>In the present study, SRR was significantly higher in patients with scrotal testis and low level of FSH and LH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Performing mTESE could be recommended in ex\u2010cryptorchid patients with post orchidopexy NOA. Preoperative testicular biopsy seems to be unnecessary while clinical criteria can perfectly define NOA.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.13463","type":"journal-article","created":{"date-parts":[[2023,5,21]],"date-time":"2023-05-21T14:34:15Z","timestamp":1684679655000},"page":"157-163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Microdissection testicular sperm extraction outcomes in azoospermic patients with bilateral orchidopexy"],"prefix":"10.1111","volume":"12","author":[{"given":"Hamid","family":"Arasteh","sequence":"first","affiliation":[{"name":"Department of Andrology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine  Tehran Iran"},{"name":"Department of Urology Shariati Hospital Faculty of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Ali Sadighi","family":"Gilani","sequence":"additional","affiliation":[{"name":"Department of Andrology Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine  Tehran Iran"},{"name":"Department of Urology Shariati Hospital Faculty of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9511-5887","authenticated-orcid":false,"given":"Mahdi","family":"Ramezani\u2010binabaj","sequence":"additional","affiliation":[{"name":"Department of Urology Shariati Hospital Faculty of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Babaei","sequence":"additional","affiliation":[{"name":"Department of Urology Shariati Hospital Faculty of Medicine Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12679"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00906"},{"key":"e_1_2_10_4_1","unstructured":"LeslieSW SajjadH VillanuevaCA Cryptorchidism. 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G\u00f6teborg: V\u00e4stra G\u00f6talandsregionen Sahlgrenska Universitetssjukhuset HTA\u2010centrum:2019. 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