{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:19:55Z","timestamp":1783937995326,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T00:00:00Z","timestamp":1689811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The minimally invasive infrapubic approach (MIIA) for inflatable penile prosthesis (IPP) placement has shown favorable peri\u2010operative safety and efficacy profile, but scarce data exist on long\u2010term follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We investigated the safety and efficacy of IPP implantation via the MIIA after a minimum 5\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>We identified data of implanted patients prospectively included in our institutional database. Complications and functional outcomes were assessed by using validated tools. Specifically, quality of life and patient satisfaction were evaluated by the Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) questionnaire. Kaplan\u2013Meier method was used to analyze IPP survival (defined as a working IPP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 67 patients implanted by MIIA with a median (IQR) age of 64 years (61\u221270) were included. The median (IQR) follow\u2010up duration was 71 months (63\u221280). Fifteen (22%) patients experienced complications: minor (Clavien \u22642) events included changes in penile sensitivity (<jats:italic>n<\/jats:italic>\u00a0=\u00a01; 1.5%), orgasmic dysfunction (<jats:italic>n<\/jats:italic>\u00a0=\u00a01; 1.5%), pain (<jats:italic>n<\/jats:italic>\u00a0=\u00a05; 7%), urinary tract infection (<jats:italic>n<\/jats:italic>\u00a0=\u00a02; 3%), and chronic discomfort (<jats:italic>n<\/jats:italic>\u00a0=\u00a01; 1.5%); major (Clavien 3) complications were represented by mechanical failure (<jats:italic>n<\/jats:italic>\u00a0=\u00a03; 4.5%), IPP infection (<jats:italic>n<\/jats:italic>\u00a0=\u00a01; 1.5%), and cylinder protrusion (<jats:italic>n<\/jats:italic>\u00a0=\u00a01; 1.5%). The estimated IPP survival was 94% (95% CI, 91.4\u221296.6), 92.5% (95% CI, 89.7\u221295.3), and 92.5% (95% CI, 89.7\u221295.3) at 3, 5, and 7 years after implantation, respectively. In patients using the device at follow\u2010up (<jats:italic>n<\/jats:italic>\u00a0=\u00a061; 91%), median (IQR) scores for QoLSPP domains demonstrated favorable functional outcomes and patient satisfaction: functional 21 (19\u221223), personal 16 (15\u221218), relational 14 (12\u221215), and social 12 (11\u221214).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and conclusion<\/jats:title><jats:p>This study represents the longest follow\u2010up using validated tools to assess the outcomes of IPP implantation via MIIA so far. IPP placement via MIIA confirms to be safe and to offer high satisfaction to both patients and partners at mid\u2010term evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.13497","type":"journal-article","created":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T12:59:18Z","timestamp":1689425958000},"page":"624-632","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Mid\u2010term outcomes of minimally invasive infrapubic approach for inflatable penile prosthesis implantation: A single\u2010center study and literature review"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2321-0548","authenticated-orcid":false,"given":"Giovanni Battista","family":"Di Pierro","sequence":"first","affiliation":[{"name":"Department of Maternal and Child Health and Urological Sciences \u2018\u2018Sapienza\u2019\u2019 University Rome 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