{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T08:02:46Z","timestamp":1783497766722,"version":"3.55.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,11,3]],"date-time":"2024-11-03T00:00:00Z","timestamp":1730592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,11,3]],"date-time":"2024-11-03T00:00:00Z","timestamp":1730592000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dietary factors and chronic gastrointestinal diseases are frequent determinants of sexual dysfunctions (SD). Whether inflammatory bowel diseases (IBD) are associated with SD is not well known as well as the role of diet and quality of life (QoL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the prevalence of SD in a cohort of IBD patients and assess the role of clinical\u2010demographic variables, adherence to Mediterranean diet (MD) and QoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This is a cross\u2010sectional observational study involving 301 patients (134 females and 167 males); 119 had Crohn's Disease and 182 had ulcerative colitis. SD were assessed through the Female Sexual Function Index (FSFI) and the International Index of Erectile Function (IIEF). Adherence to MD was evaluated by the MD Score. QoL was investigated by the 12\u2010item Short\u2010Form Health Survey (SF\u201012) which yields summary scores of physical (PCS) and mental (MCS) health. Multiple logistic regression was used to identify predictors of SD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Prevalence of SD in females was 61.9%, while 52.1% of males had erectile dysfunction. No differences in the prevalence of SD were found between CD and UC in both males and females. IBD activity, as defined by patient\u2010reported outcomes, was significantly associated with SD in both sexes. In females, MD adherence score (OR 0.8, 95% CI 0.653\u20130.974,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.027), PCS (OR\u00a0=\u00a00.936, CI 95%\u00a0=\u00a00.891\u20130.983,\n                      <jats:italic>p\u00a0<\/jats:italic>\n                      =\u00a00.008), and MCS (OR 0.9, 95% CI 0.906\u20130.985,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.008) were protective against SD, whereas in males a higher PCS was associated with a lower probability of SD (OR 0.9, 95% CI 0.891\u20130.978,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.004)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>IBD patients had a significant prevalence of SD which occurred more frequently in females than in males. Disease activity is associated with a higher likelihood of SD in both sexes, whereas dietary factors are differentially associated with SD in males and females. A better QoL is associated with a lower risk of SD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SD is prevalent among men and women with IBD. Adherence to MD, PCS and MCS in females as well as PCS in males were protective against SD. The assessment of sexual function in IBD patients could be relevant in order to reach an early diagnosis and a timely treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.13791","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T02:35:38Z","timestamp":1730687738000},"page":"1693-1701","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Sexual dysfunctions in inflammatory bowel disease: role of Mediterranean diet and quality of life"],"prefix":"10.1111","volume":"13","author":[{"given":"Lorenzo","family":"Romano","sequence":"first","affiliation":[{"name":"Department of Neurosciences Reproductive Sciences and Odontostomatology and Urology Unit Federico II University  Naples Italy"},{"name":"Department of Woman Child and General and Specialized Surgery and Urology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Fonticelli","sequence":"additional","affiliation":[{"name":"Department of Precision Medicine and Hepatogastroenterology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnese","family":"Miranda","sequence":"additional","affiliation":[{"name":"Gastroenterology Unit AORN V. Monaldi  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kateryna","family":"Priadko","sequence":"additional","affiliation":[{"name":"Department of Precision Medicine and Hepatogastroenterology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Reproductive Sciences and Odontostomatology and Urology Unit Federico II University  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4315-7660","authenticated-orcid":false,"given":"Felice","family":"Crocetto","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Reproductive Sciences and Odontostomatology and Urology Unit Federico II University  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4884-132X","authenticated-orcid":false,"given":"Biagio","family":"Barone","sequence":"additional","affiliation":[{"name":"Department of Neurosciences Reproductive Sciences and Odontostomatology and Urology Unit Federico II University  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Arcaniolo","sequence":"additional","affiliation":[{"name":"Department of Woman Child and General and Specialized Surgery and Urology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1175-8637","authenticated-orcid":false,"given":"Lorenzo","family":"Spirito","sequence":"additional","affiliation":[{"name":"Department of Woman Child and General and Specialized Surgery and Urology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celeste","family":"Manfredi","sequence":"additional","affiliation":[{"name":"Department of Woman Child and General and Specialized Surgery and Urology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonietta Gerarda","family":"Gravina","sequence":"additional","affiliation":[{"name":"Department of Precision Medicine and Hepatogastroenterology Unit University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmine","family":"Sciorio","sequence":"additional","affiliation":[{"name":"Urology Unit A. 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