{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T10:49:16Z","timestamp":1753181356755,"version":"3.41.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Vasectomy is a safe and effective form of contraception. However, fear of altered sexual function is still associated with vasectomy in many men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the prevalence of vasectomy among middle\u2010aged men in Germany and to investigate possible associations between a previous vasectomy and sexual dysfunctions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data on lifestyle, sexual activity, satisfaction, and dysfunction from 5425 middle\u2010aged, heterosexual men were collected. Differences between vasectomized (VM) and non\u2010vasectomized men (NVM) were assessed. Multiple logistic regression analyses were calculated to determine variables associated with erectile dysfunction (ED), premature ejaculation (PE), and low libido.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>5425 men with a mean age of 50.6\u00a0\u00b1\u00a00.8 years were included in this analysis. Vasectomy was performed in 12.5% (679\/5425) on average 8.6\u00a0\u00b1\u00a05.8 years ago. 84.4% were sexually active in the last 3 months (93.0% in vasectomized men vs. 83.2% in non\u2010vasectomized men; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and 45.4% were satisfied with their sexual life (55.2% in vasectomized men vs. 44.0% in non\u2010vasectomized men; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). The prevalence of erectile dysfunction was significantly lower in vasectomized men (12.1%\u00a0vs. 20.1%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and a previous vasectomy was associated with a decreased risk for erectile dysfunction in multivariable regression analysis (OR: 0.65 [0.40\u20130.83]). The prevalence of low libido (4.7% in vasectomized men vs. 7.1% in non\u2010vasectomized men; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.02) was marginally higher among non\u2010vasectomized men. The prevalence of premature ejaculation (7.1% in vasectomized men vs. 6.1% in non\u2010vasectomized men, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.5) did not differ significantly between vasectomized and non\u2010vasectomized men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>A previous vasectomy is not associated with an increased risk for sexual dysfunction, and vasectomized middle\u2010aged men are more sexually active and satisfied compared to their non\u2010vasectomized counterparts. The main limitations are the retrospective design and missing pre\u2010vasectomy data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Men can be reassured that the fear of sexual dysfunctions and diminished sex life after a vasectomy is unwarranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.13804","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T12:08:36Z","timestamp":1731672516000},"page":"665-674","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Associations of vasectomy with sexual dysfunctions and the sex life of middle\u2010aged men"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5895-2595","authenticated-orcid":false,"given":"Matthias","family":"Jahnen","sequence":"first","affiliation":[{"name":"Department of Urology Klinikum rechts der Isar School of Medicine Technical University of Munich  Munich 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