{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:47:11Z","timestamp":1790214431298,"version":"4.1.0"},"reference-count":95,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:00:00Z","timestamp":1735603200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence indicates a wide range of andrological alterations in patients with the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS\u2010CoV\u20102) infection and Coronavirus Disease 2019 (COVID\u201019).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To provide an update on the andrological effects of SARS\u2010CoV\u20102 infection and COVID\u201019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>PubMed\/MEDLINE and Institutional websites were searched for randomized clinical trials, non\u2010systematic reviews, systematic reviews, and meta\u2010analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010four records were included from 2020 to 2024. The most representative paper categories were non\u2010systematic reviews (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a026) and systematic reviews\/meta\u2010analyses (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a027). One randomized, prospective, phase 2 trial was also included. Eight topics were identified and discussed as follows: short\u2010 and long\u2010term seminal changes attributable to SARS\u2010CoV\u20102 infection or COVID\u201019; andrological effects of anti\u2010SARS\u2010CoV\u20102 vaccines; the potential impact of SARS\u2010CoV\u20102 infection and COVID\u201019 on male fertility; the relationship between serum testosterone levels and COVID\u201019 prognosis in men; fertility care during the pandemic; urinary\/genital male system tract impairment in SARS\u2010CoV\u20102 infection and COVID\u201019; the effect of SARS\u2010CoV\u20102 infection and COVID\u201019 on circulating levels of sex steroid hormones; the impact of SARS\u2010CoV\u20102 and COVID\u201019 on sexual function and activity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>SARS\u2010CoV\u20102 can affect the whole testicular function through direct and indirect mechanisms, with a positive relation between the severity of SARS\u2010CoV\u20102 infection and the level of deterioration of testicular function. Testicular function recovers along with the recovery from the disease. In vitro fertilization techniques ensure similar results in patients with or without previous SARS\u2010CoV\u20102 infection or COVID\u201019. Immunization with anti\u2010SARS\u2010CoV\u20102 vaccines prevents andrological complaints due to naturally occurring infection. Erectile dysfunction and sexual dysfunction are frequently diagnosed in COVID\u201019 patients due to several contributing factors, including hormonal imbalance and psychosocial complaints related to the pandemic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.13830","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T07:18:38Z","timestamp":1735629518000},"page":"1672-1682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Update on andrological effects of SARS\u2010CoV\u20102 infection and COVID\u201019: An overview review"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6521-8578","authenticated-orcid":false,"given":"Giuseppe","family":"Lisco","sequence":"first","affiliation":[{"name":"Interdisciplinary Department of Medicine School of Medicine University of Bari \u201cAldo Moro\u201d  Bari 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