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Despite vast clinical knowledge, the training of andrologists often lacks fundamental basics in medical genetics. This work, as part of the Special Issue of Andrology \u201cGenetics in Andrology\u201d, provides the core terminology in medical genetics and technological advancements in genomics, required to understand the ever\u2010progressing research in the field. It also gives an overview of study designs and approaches that have frequently led to discoveries in androgenetics. The rapid progress in the methodological toolbox in human genetics is illustrated by numerous examples of impactful androgenetic studies over 60 years, and their clinical implications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/andr.13835","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T06:58:47Z","timestamp":1736405927000},"page":"986-998","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Introduction to androgenetics: terminology, approaches, and impactful studies across 60 years"],"prefix":"10.1111","volume":"13","author":[{"given":"Arvand","family":"Akbari","sequence":"first","affiliation":[{"name":"Center for Embryonic Cell &amp; Gene Therapy Oregon Health &amp; Science University  Portland Oregon USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Kasak","sequence":"additional","affiliation":[{"name":"Chair of Human Genetics, Institute of 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