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However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post\u2010natal testis development and in the mature testis. Therefore, to specifically learn more about human testis development and function, there is a need to use human testis tissue for research. Human testicular tissues that have been donated for research have allowed extensive molecular and cytological assessments, as well as single\u2010cell transcriptome and epigenome analyses. These tissues have also been used for the development of cell technologies and in vitro models that aim to improve infertility treatments and diagnostics. Biopsied material taken from patients and designated for research is usually very small in size and is unsuitable for comprehensive studies. On the other hand, research using whole testes obtained from deceased, deidentified donors has become a valuable resource to assess conservation between humans and other organisms and identify human\u2010specific phenomena. This review discusses the acquisition of donated deidentified human testes and their use for basic science research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.70008","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T07:56:37Z","timestamp":1738828597000},"page":"2359-2372","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The use of deidentified organ donor testes for research"],"prefix":"10.1111","volume":"14","author":[{"given":"Marina V.","family":"Pryzhkova","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology Uniformed Services University of the Health Sciences  Bethesda Maryland USA"},{"name":"The Henry M. 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