{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T07:37:49Z","timestamp":1777275469751,"version":"3.51.4"},"reference-count":43,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T00:00:00Z","timestamp":1777161600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJSC21U6"],"award-info":[{"award-number":["JPMJSC21U6"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>History of childhood sexual abuse (CSA) may affect adult male sexual function, yet population\u2010based evidence remains limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to evaluate the associations between a history of CSA and recent sexual function outcomes, specifically self\u2010reported erectile difficulties and decreased libido, and to examine differences by age group and cohabitation status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>We analyzed data from 8837 men aged 18\u201379 years who participated in the 2023 JACSIS study, a population\u2010based online survey in Japan. CSA before age 18 years was identified using behavior\u2010specific items and two direct screening questions. Outcomes were defined as binary measures of self\u2010reported erectile difficulties and decreased libido. We adjusted for confounding using inverse probability of treatment weighting (IPTW) based on prespecified propensity scores. Effect modification by age group and cohabitation status was tested. Secondary analyses included depression, anxiety, and sleep problems to evaluate the attenuation of associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 8837 eligible men, 667 (7.5%) reported CSA. CSA was associated with significantly higher odds of self\u2010reported erectile difficulties (adjusted odds ratio [aOR] 3.14, 95% confidence interval [CI] 2.61\u20133.78,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001) and decreased libido (aOR 2.83, 95% CI 2.37\u20133.38,\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Stratified analyses showed consistent associations across all age groups and cohabitation statuses, with no significant effect modification detected. Simultaneous adjustment for depression, anxiety, and sleep problems attenuated these associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The associations observed across age groups suggest that CSA appears to have a lasting and independent negative impact on male sexual function. These findings imply that the consequences of early trauma may persist throughout adulthood, involving mechanisms beyond concurrent mental health or sleep burdens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CSA history is significantly associated with self\u2010reported male sexual difficulties. Integrating trauma\u2010informed care and routine screening for psychological and sleep comorbidities into urological practice is essential for comprehensive patient management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.70244","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T06:41:04Z","timestamp":1777272064000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Childhood Sexual Abuse and Self\u2010Reported Erectile Difficulties in Adult Men"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-7626","authenticated-orcid":false,"given":"Yousuke","family":"Imanishi","sequence":"first","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4019-8271","authenticated-orcid":false,"given":"Maria","family":"Iorini","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Wada","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Studies Faculty of International Liberal Arts Dokkyo University  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3883-0865","authenticated-orcid":false,"given":"Sinchul","family":"Jwa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Osaka Metropolitan University  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Tabuchi","sequence":"additional","affiliation":[{"name":"Division of Epidemiology School of Public Health Tohoku University Graduate School of Medicine  Miyagi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mai","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Department of Psychiatry Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,26]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.6.537"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sxmr.2019.06.008"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/sexmed\/qfaf072"},{"issue":"1","key":"e_1_2_13_5_1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10896-010-9340-6","article-title":"The Effect of Childhood Sexual Abuse on Psychosexual Functioning During Adulthood","volume":"26","author":"Easton S. 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