{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T12:14:14Z","timestamp":1783512854583,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Ischaemic priapism (IP) is a urological emergency that can lead to erectile dysfunction (ED) if not treated promptly. This study aims to evaluate and compare clinical outcomes between early and delayed penile prosthesis insertion in patients with IP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a single centre retrospective observational study, which included 166 patients who underwent penile prosthesis surgery for refractory IP from 2006 to 2025. Data were collected through institutional databases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Findings and Limitations<\/jats:title>\n                    <jats:p>Early prosthesis insertion was performed in 112 patients, with a median time (IQR) to implantation of 10 (6\u201315) days. 54 patients underwent delayed insertion, with a median time of 270 (120\u20131460) days. In unadjusted analysis, patient satisfaction was higher in the early group (OR 2.93; 95% CI: 1.21\u20137.18); however, this became a non\u2010significant trend after multivariable adjustment for prosthesis type. Delayed implantation remained independently associated with higher odds of revision surgery after adjustment for prosthesis type (OR 3.74; 95% CI: 1.22\u201311.44) There were no statistically significant differences between reported penile shortening and post\u2010operative infection. Key limitations include the study's retrospective single\u2010centre design, differential follow\u2010up duration and the lack of a standardized questionnaire to assess patient satisfaction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Patients in both early and delayed group underwent penile prosthesis implantation, either a malleable or inflatable prosthesis was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Implications<\/jats:title>\n                    <jats:p>The findings from this study highlight the importance of timely management of IP in clinical settings. Early penile prosthesis insertion is associated with lower revision risk and demonstrates a trend toward improved satisfaction. The findings support a proactive surgical approach towards patients with refractory IP, underscoring the importance of prompt management when conservative treatment fails.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.70309","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T11:20:56Z","timestamp":1783509656000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Outcomes of Early versus Delayed Penile Prosthesis Insertion in Patients With Ischaemic Priapism\u2014Long\u2010Term Outcome Experience From a Single High\u2010volume Centre"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7377-4619","authenticated-orcid":false,"given":"King Sum","family":"Tong","sequence":"first","affiliation":[{"name":"The University of Hong Kong  Hong Kong China"},{"name":"King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5703-2319","authenticated-orcid":false,"given":"Karl H.","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Urology Chelsea and Westminster Hospital NHS Trust  London UK"},{"name":"Division of Surgery and Interventional Science University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3291-6779","authenticated-orcid":false,"given":"Jerry T. Y.","family":"Lau","sequence":"additional","affiliation":[{"name":"The University of Hong Kong  Hong Kong China"},{"name":"King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Ralph","sequence":"additional","affiliation":[{"name":"The Institute of Andrology Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2958-1614","authenticated-orcid":false,"given":"Asif","family":"Muneer","sequence":"additional","affiliation":[{"name":"Division of Surgery and Interventional Science University College London  London UK"},{"name":"The Institute of Andrology Department of Urology University College London Hospitals NHS Foundation Trust  London UK"},{"name":"National Institute for Health and Research University College London Hospitals, Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6364-0310","authenticated-orcid":false,"given":"Hussain M.","family":"Alnajjar","sequence":"additional","affiliation":[{"name":"Division of Surgery and Interventional Science University College London  London UK"},{"name":"The Institute of Andrology Department of Urology University College London Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"754","article-title":"Acute Ischemic Priapism: An AUA\/SMSNA Guideline","volume":"207","author":"Bivalacqua T. 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