{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:58:29Z","timestamp":1790423909882,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:00:00Z","timestamp":1790380800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although the association between erectile dysfunction (ED) and cardiovascular disease is well established, its prevalence in patients with atherosclerosis remains poorly defined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate ED prevalence, severity, and associated risk factors (RFs) in patients with atherosclerotic disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This single\u2010centre, cross\u2010sectional, non\u2010randomised observational study included male patients referred to a vascular surgery service with documented atherosclerotic disease. Erectile function was assessed using the International Index of Erectile Function\u201015 questionnaire, and RFs were analysed using univariable and multivariable regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 162 patients were enrolled (mean age, 70.1 \u00b1 8.6 years); ED was present in 93.8%, with severe ED observed in 62.3%. Multivariable analysis confirmed age as a significant RF for ED, particularly &gt; 75 years, while age, diabetes mellitus, and subjective ED duration were significantly associated with greater severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The high prevalence of ED supports its role as a manifestation of systemic vascular disease linked to endothelial dysfunction and diffuse atherosclerosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ED is highly prevalent among patients with clinically overt atherosclerotic disease requiring vascular surgery referral, and may represent a marker of systemic vascular pathology. Routine assessment of sexual function may improve cardiovascular risk stratification and preventive management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/andr.70406","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:09:07Z","timestamp":1790420947000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cross\u2010Sectional Study of the PREValence of Erectile DysfunctIon in the Arteriopathic Population (PREVEDI)"],"prefix":"10.1111","author":[{"given":"Luca","family":"Farchioni","sequence":"first","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"},{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7897-146X","authenticated-orcid":false,"given":"Andrea","family":"Ferri","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"},{"name":"Clinical and Experimental Medicine PhD Program University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6424-212X","authenticated-orcid":false,"given":"Nicola","family":"Leone","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2902-1329","authenticated-orcid":false,"given":"Mattia","family":"Migliari","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"},{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi Alberto Maria","family":"Bartolotti","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Santi","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"},{"name":"Unit of Endocrinology, Department of Medical Specialties Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7089-7330","authenticated-orcid":false,"given":"Giorgia","family":"Spaggiari","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"},{"name":"Unit of Endocrinology, Department of Medical Specialties Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Silingardi","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"},{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4860-1636","authenticated-orcid":false,"given":"Stefano","family":"Gennai","sequence":"additional","affiliation":[{"name":"Unit of Vascular Surgery, Department of Nephrological, Cardiac and Vascular Diseases Azienda Ospedaliero\u2010Universitaria of Modena  Modena Italy"},{"name":"Department of Biomedical, Metabolic and Neuro Sciences University of Modena and Reggio Emilia (UNIMORE)  Modena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13132"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41443\u2010025\u201001037\u20102"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1148834"},{"key":"e_1_2_9_5_1","volume-title":"StatPearls","author":"Leslie S. W.","year":"2025"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26073073"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.89918"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354931"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2020.10.021"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-98580-5_7"},{"issue":"10","key":"e_1_2_9_11_1","first-page":"820","article-title":"Erectile Dysfunction","volume":"94","author":"Rew K. T.","year":"2016","journal-title":"American Family Physician"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00270\u2010012\u20100520\u2010z"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/17446651.2025.2469635"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/sxmrev\/qeae066"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.79292"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020\u2010024\u201004020\u2010x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13778"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau\u20102024\u2010751"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2025.1543668"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.36740\/WLek202009229"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1714\/2372.25474"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/sxmrev\/qeaf014"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.82125"},{"issue":"1","key":"e_1_2_9_24_1","first-page":"86","article-title":"Role of Arteriography and Percutaneous Transluminal Angioplasty in the Diagnosis and Treatment of Arterial Vasculogenic Impotence]","volume":"88","author":"Urigo F.","year":"1994","journal-title":"Journal of Radiology in Medicine"},{"issue":"10","key":"e_1_2_9_25_1","first-page":"435","article-title":"Results of the Treatment of Vascular\u2010Induced Impotence Using PTA","volume":"43","author":"Mielecki T.","year":"1990","journal-title":"R\u00f6ntgen\u2010Bl\u00e4tter; Zeitschrift f\u00fcr R\u00f6ntgen\u2010Technik und medizinisch\u2010wissenschaftliche Photographie"},{"issue":"2","key":"e_1_2_9_26_1","first-page":"75","article-title":"Selective Arteriography in the Study of Arterial Vasculogenic Impotence","volume":"64","author":"Urigo F.","year":"1992","journal-title":"Archivio Italiano di Urologia, Nefrologia e Andrologia"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.CON.0000446104.90043.a5"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.307611"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.07.006"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.11.013"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u20101241.2010.02410.x"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15313"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.13169"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.847519"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.05.005"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12875\u2010020\u201001238\u20102"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201105"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100034\u20101393976"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2025.06.010"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2022.04.011"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.16042"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287216685027"}],"container-title":["Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/andr.70406","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/andr.70406","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/andr.70406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:09:08Z","timestamp":1790420948000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/andr.70406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,26]]},"references-count":41,"alternative-id":["10.1111\/andr.70406"],"URL":"https:\/\/doi.org\/10.1111\/andr.70406","archive":["Portico"],"relation":{},"ISSN":["2047-2919","2047-2927"],"issn-type":[{"value":"2047-2919","type":"print"},{"value":"2047-2927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,26]]},"assertion":[{"value":"2026-05-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"andr.70406"}}