{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:53:23Z","timestamp":1789955603528,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T00:00:00Z","timestamp":1467936000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T00:00:00Z","timestamp":1467936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["221-2011-5216"],"award-info":[{"award-number":["221-2011-5216"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neurol Scand"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1111\/ane.12636","type":"journal-article","created":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T06:34:59Z","timestamp":1467959699000},"page":"576-584","source":"Crossref","is-referenced-by-count":55,"title":["Cerebrospinal fluid and blood flow patterns in idiopathic normal pressure hydrocephalus"],"prefix":"10.1155","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1454-4725","authenticated-orcid":false,"given":"S.","family":"Qvarlander","sequence":"first","affiliation":[{"name":"Department of Radiation Sciences; Ume\u00e5 University; Ume\u00e5 Sweden"},{"name":"Centre for Biomedical Engineering and Physics; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Ambarki","sequence":"additional","affiliation":[{"name":"Department of Radiation Sciences; Ume\u00e5 University; Ume\u00e5 Sweden"},{"name":"Centre for Biomedical Engineering and Physics; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"W\u00e5hlin","sequence":"additional","affiliation":[{"name":"Department of Radiation Sciences; Ume\u00e5 University; Ume\u00e5 Sweden"},{"name":"Ume\u00e5 Centre for Functional Brain Imaging; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Jacobsson","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Clinical Neuroscience; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Birgander","sequence":"additional","affiliation":[{"name":"Department of Radiation Sciences; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Malm","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Clinical Neuroscience; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Eklund","sequence":"additional","affiliation":[{"name":"Department of Radiation Sciences; Ume\u00e5 University; Ume\u00e5 Sweden"},{"name":"Centre for Biomedical Engineering and Physics; Ume\u00e5 University; Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,8]]},"reference":[{"key":"10.1111\/ane.12636-BIB0001|ane12636-cit-0001","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01.rli.0000100892.87214.49","article-title":"Relationship Between Cerebrospinal Fluid and Blood Dynamics in Healthy Volunteers and Patients with Communicating Hydrocephalus","volume":"39","author":"Bal\u00e9dent","year":"2004","journal-title":"Invest Radiol"},{"key":"10.1111\/ane.12636-BIB0002|ane12636-cit-0002","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s00701-007-1142-0","article-title":"Can MR measurement of intracranial hydrodynamics and compliance differentiate which patient with idiopathic normal pressure hydrocephalus will improve following shunt insertion?","volume":"149","author":"Bateman","year":"2007","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1111\/ane.12636-BIB0003|ane12636-cit-0003","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1177\/028418519403500302","article-title":"MR imaging of cerebrospinal fluid dynamics in health and disease. On the vascular pathogenesis of communicating hydrocephalus and benign intracranial hypertension","volume":"35","author":"Greitz","year":"1994","journal-title":"Acta Radiol"},{"key":"10.1111\/ane.12636-BIB0004|ane12636-cit-0004","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/BF00588133","article-title":"Cerebrospinal fluid flow and production in patients with normal pressure hydrocephalus studied by MRI","volume":"36","author":"Gideon","year":"1994","journal-title":"Neuroradiology"},{"key":"10.1111\/ane.12636-BIB0005|ane12636-cit-0005","first-page":"534","article-title":"Measurement of cerebrospinal fluid flow at the cerebral aqueduct by use of phase-contrast magnetic resonance imaging: technique validation and utility in diagnosing idiopathic normal pressure hydrocephalus","volume":"50","author":"Luetmer","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1111\/ane.12636-BIB0006|ane12636-cit-0006","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1007\/s00330-002-1697-3","article-title":"Frequency analyses of CSF flow on cine MRI in normal pressure hydrocephalus","volume":"13","author":"Miyati","year":"2003","journal-title":"Eur Radiol"},{"key":"10.1111\/ane.12636-BIB0007|ane12636-cit-0007","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10143-004-0326-9","article-title":"Radiological assessment of hydrocephalus: new theories and implications for therapy","volume":"27","author":"Greitz","year":"2004","journal-title":"Neurosurg Rev"},{"key":"10.1111\/ane.12636-BIB0008|ane12636-cit-0008","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.3174\/ajnr.A4340","article-title":"Aqueductal stroke volume: comparisons with intracranial pressure scores in idiopathic normal pressure hydrocephalus","volume":"36","author":"Ringstad","year":"2015","journal-title":"AJNR Am J Neuroradiol"},{"issue":"S2","key":"10.1111\/ane.12636-BIB0009|ane12636-cit-0009","first-page":"17","article-title":"The value of supplemental prognostic tests for the preoperative assessment of idiopathic normal-pressure hydrocephalus","volume":"57","author":"Marmarou","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1111\/ane.12636-BIB0010|ane12636-cit-0010","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s004150050003","article-title":"Diagnosis and management of normal-pressure hydrocephalus","volume":"247","author":"Vanneste","year":"2000","journal-title":"J Neurol"},{"key":"10.1111\/ane.12636-BIB0011|ane12636-cit-0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2010.12.JNS10926","article-title":"Ventricle wall movements and cerebrospinal fluid flow in hydrocephalus","volume":"115","author":"Penn","year":"2011","journal-title":"J Neurosurg"},{"key":"10.1111\/ane.12636-BIB0012|ane12636-cit-0012","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.3171\/2015.6.JNS15496","article-title":"Phase-contrast magnetic resonance imaging reveals net retrograde aqueductal flow in idiopathic normal pressure hydrocephalus","volume":"124","author":"Ringstad","year":"2016","journal-title":"J Neurosurg"},{"key":"10.1111\/ane.12636-BIB0013|ane12636-cit-0013","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/2045-8118-8-12","article-title":"Cerebrospinal fluid and blood flow in mild cognitive impairment and Alzheimer's disease: a differential diagnosis from idiopathic normal pressure hydrocephalus","volume":"8","author":"ElSankari","year":"2011","journal-title":"Fluids Barriers CNS"},{"key":"10.1111\/ane.12636-BIB0014|ane12636-cit-0014","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s003810050440","article-title":"Quantitative assessment of cerebrospinal fluid hydrodynamics using a phase-contrast cine MR image in hydrocephalus","volume":"15","author":"Kim","year":"1999","journal-title":"Childs Nerv Syst"},{"issue":"S2","key":"10.1111\/ane.12636-BIB0015|ane12636-cit-0015","first-page":"4","article-title":"Diagnosing idiopathic normal-pressure hydrocephalus","volume":"57","author":"Relkin","year":"2005","journal-title":"Neurosurgery"},{"key":"10.1111\/ane.12636-BIB0016|ane12636-cit-0016","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1212\/WNL.0b013e31820f2dd0","article-title":"Reference values for CSF outflow resistance and intracranial pressure in healthy elderly","volume":"76","author":"Malm","year":"2011","journal-title":"Neurology"},{"key":"10.1111\/ane.12636-BIB0017|ane12636-cit-0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2342-10-1","article-title":"Design and validation of Segment-freely available software for cardiovascular image analysis","volume":"10","author":"Heiberg","year":"2010","journal-title":"BMC Med Imaging"},{"key":"10.1111\/ane.12636-BIB0018|ane12636-cit-0018","first-page":"447","article-title":"Arterial assessment by doppler-shift ultrasound","volume":"67","author":"Gosling","year":"1974","journal-title":"Proc R Soc Med"},{"key":"10.1111\/ane.12636-BIB0019|ane12636-cit-0019","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/jmri.23527","article-title":"Phase contrast MRI quantification of pulsatile volumes of brain arteries, veins, and cerebrospinal fluids compartments: repeatability and physiological interactions","volume":"35","author":"W\u00e5hlin","year":"2012","journal-title":"J Magn Reson Imaging"},{"key":"10.1111\/ane.12636-BIB0020|ane12636-cit-0020","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/00004424-200107000-00003","article-title":"Cerebrospinal fluid dynamics and relation with blood flow: a magnetic resonance study with semiautomated cerebrospinal fluid segmentation","volume":"36","author":"Bal\u00e9dent","year":"2001","journal-title":"Invest Radiol"},{"key":"10.1111\/ane.12636-BIB0021|ane12636-cit-0021","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.3174\/ajnr.A2166","article-title":"Assessment of craniospinal pressure-volume indices","volume":"31","author":"W\u00e5hlin","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/ane.12636-BIB0022|ane12636-cit-0022","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1002\/jmri.20722","article-title":"Brain hydrodynamics study by phase-contrast magnetic resonance imaging and transcranial color doppler","volume":"24","author":"Bal\u00e9dent","year":"2006","journal-title":"J Magn Reson Imaging"},{"key":"10.1111\/ane.12636-BIB0023|ane12636-cit-0023","first-page":"1301","article-title":"Cerebrospinal fluid flow measured by phase-contrast cine MR","volume":"14","author":"Enzmann","year":"1993","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/ane.12636-BIB0024|ane12636-cit-0024","first-page":"389","article-title":"Analysis of cerebrospinal fluid flow waveforms with gated phase-contrast MR velocity measurements","volume":"16","author":"Bhadelia","year":"1995","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/ane.12636-BIB0025|ane12636-cit-0025","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1227\/01.NEU.0000370939.30003.D1","article-title":"Brain ventricular size in healthy elderly: comparison between Evans index and volume measurement","volume":"67","author":"Ambarki","year":"2010","journal-title":"Neurosurgery"},{"key":"10.1111\/ane.12636-BIB0026|ane12636-cit-0026","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.neuroimage.2015.07.073","article-title":"Dynamics of respiratory and cardiac CSF motion revealed with real-time simultaneous multi-slice EPI velocity phase contrast imaging","volume":"122","author":"Chen","year":"2015","journal-title":"Neuroimage"},{"key":"10.1111\/ane.12636-BIB0027|ane12636-cit-0027","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/ane.12246","article-title":"Repeatability of cerebrospinal fluid constant rate infusion study","volume":"130","author":"Swallow","year":"2014","journal-title":"Acta Neurol Scand"},{"key":"10.1111\/ane.12636-BIB0028|ane12636-cit-0028","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/ane.12541","article-title":"Intracranial pressure, its components and cerebrospinal fluid pressure-volume compensation","volume":"134","author":"Kasprowicz","year":"2016","journal-title":"Acta Neurol Scand"},{"key":"10.1111\/ane.12636-BIB0029|ane12636-cit-0029","first-page":"1277","article-title":"CSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry","volume":"19","author":"Kitagaki","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1111\/ane.12636-BIB0030|ane12636-cit-0030","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1743-8454-7-18","article-title":"Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study","volume":"7","author":"Hashimoto","year":"2010","journal-title":"Cerebrospinal Fluid Res"},{"key":"10.1111\/ane.12636-BIB0031|ane12636-cit-0031","doi-asserted-by":"crossref","first-page":"e37502","DOI":"10.1371\/journal.pone.0037502","article-title":"Age-specific characteristics and coupling of cerebral arterial inflow and cerebrospinal fluid dynamics","volume":"7","author":"Schmid Daners","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/ane.12636-BIB0032|ane12636-cit-0032","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1038\/sj.jcbfm.9600462","article-title":"Aging effects on cerebral blood and cerebrospinal fluid flows","volume":"27","author":"Stoquart-ElSankari","year":"2007","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1111\/ane.12636-BIB0033|ane12636-cit-0033","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1034\/j.1600-0404.2001.00092.x","article-title":"Normal pressure hydrocephalus and cerebral blood flow: a review","volume":"104","author":"Owler","year":"2001","journal-title":"Acta Neurol Scand"},{"key":"10.1111\/ane.12636-BIB0034|ane12636-cit-0034","doi-asserted-by":"crossref","DOI":"10.1177\/0271678X16629486","article-title":"Aging alters the dampening of pulsatile blood flow in cerebral arteries","author":"Zarrinkoob","year":"2016","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1111\/ane.12636-BIB0035|ane12636-cit-0035","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/BF00596493","article-title":"Pulsatile brain movement and associated hydrodynamics studied by magnetic resonance phase imaging The Monro-Kellie doctrine revisited","volume":"34","author":"Greitz","year":"1992","journal-title":"Neuroradiology"},{"key":"10.1111\/ane.12636-BIB0036|ane12636-cit-0036","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1148\/radiology.217.3.r00dc42877","article-title":"MR-Intracranial pressure (ICP): a method to measure intracranial elastance and pressure noninvasively by means of MR imaging: baboon and human study","volume":"217","author":"Alperin","year":"2000","journal-title":"Radiology"},{"key":"10.1111\/ane.12636-BIB0037|ane12636-cit-0037","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1002\/jmri.20999","article-title":"Noninvasive MRI assessment of intracranial compliance in idiopathic normal pressure hydrocephalus","volume":"26","author":"Miyati","year":"2007","journal-title":"J Magn Reson Imaging"},{"key":"10.1111\/ane.12636-BIB0038|ane12636-cit-0038","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1148\/radiol.13130840","article-title":"Arterial, venous, and cerebrospinal fluid flow: simultaneous assessment with Bayesian multipoint velocity-encoded MR imaging","volume":"270","author":"Knobloch","year":"2014","journal-title":"Radiology"},{"key":"10.1111\/ane.12636-BIB0039|ane12636-cit-0039","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.inat.2015.06.004","article-title":"Continuous positive airway pressure alters cranial blood flow and cerebrospinal fluid dynamics at the craniovertebral junction","volume":"2","author":"Yiallourou","year":"2015","journal-title":"Interdiscip Neurosurg"}],"container-title":["Acta Neurologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.12636","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.12636","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ane.12636\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:49:53Z","timestamp":1671540593000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ane.12636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,8]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"URL":"https:\/\/doi.org\/10.1111\/ane.12636","archive":["Portico"],"relation":{},"ISSN":["0001-6314"],"issn-type":[{"value":"0001-6314","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7,8]]}}}