{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:24:54Z","timestamp":1761513894305},"reference-count":26,"publisher":"Hindawi Limited","issue":"5","license":[{"start":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T00:00:00Z","timestamp":1476748800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T00:00:00Z","timestamp":1476748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neurol Scand"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1111\/ane.12698","type":"journal-article","created":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T04:12:43Z","timestamp":1476850363000},"page":"533-539","source":"Crossref","is-referenced-by-count":10,"title":["Efficacy and tolerability of anti-epileptic drugs-an internet study"],"prefix":"10.1155","volume":"135","author":[{"given":"U. C.","family":"Wieshmann","sequence":"first","affiliation":[{"name":"The Walton Centre for Neurology and Neurosurgery and University of Liverpool; Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Baker","sequence":"additional","affiliation":[{"name":"The Walton Centre for Neurology and Neurosurgery and University of Liverpool; Liverpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2016,10,18]]},"reference":[{"key":"10.1111\/ane.12698-BIB0001|ane12698-cit-0001","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0920-1211(00)00124-8","article-title":"Assessing risk to benefit ratio in antiepileptic drug therapy","volume":"41","author":"Perucca","year":"2000","journal-title":"Epilepsy Res"},{"key":"10.1111\/ane.12698-BIB0002|ane12698-cit-0002","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1365-2125.2005.02554.x","article-title":"Comparison of hospital episodes with drug-induced disorders and spontaneously reported adverse drug reactions","volume":"61","author":"Barrow","year":"2005","journal-title":"Br J Clin Pharmacol"},{"key":"10.1111\/ane.12698-BIB0003|ane12698-cit-0003","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1600-0404.2011.01488.x","article-title":"Self-reported symptoms in patients on antiepileptic drugs in monotherapy","volume":"124","author":"Wieshmann","year":"2011","journal-title":"Acta Neurol Scand"},{"key":"10.1111\/ane.12698-BIB0004|ane12698-cit-0004","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1212\/WNL.62.1.23","article-title":"Systematic screening allows reduction of adverse antiepileptic drug effects: a randomized trial","volume":"62","author":"Gilliam","year":"2004","journal-title":"Neurology"},{"key":"10.1111\/ane.12698-BIB0005|ane12698-cit-0005","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1528-1157.1997.tb01128.x","article-title":"Quality of life of people with epilepsy: a European study","volume":"38","author":"Baker","year":"1997","journal-title":"Epilepsia"},{"key":"10.1111\/ane.12698-BIB0006|ane12698-cit-0006","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1212\/01.wnl.0000259411.78423.50","article-title":"Quality of life outcomes of immediate or delayed treatment of early epilepsy and single seizures","volume":"68","author":"Jacoby","year":"2007","journal-title":"Neurology"},{"key":"10.1111\/ane.12698-BIB0007|ane12698-cit-0007","first-page":"145","volume-title":"The Medical Treatment Of Epilepsy","author":"Janz","year":"1992"},{"key":"10.1111\/ane.12698-BIB0008|ane12698-cit-0008","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1212\/WNL.55.8.1106","article-title":"Do carbamazepine and phenytoin aggravate juvenile myoclonic epilepsy?","volume":"55","author":"Genton","year":"2000","journal-title":"Neurology"},{"key":"10.1111\/ane.12698-BIB0009|ane12698-cit-0009","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S0140-6736(07)60461-9","article-title":"The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial","volume":"369","author":"Marson","year":"2007","journal-title":"Lancet"},{"key":"10.1111\/ane.12698-BIB0010|ane12698-cit-0010","first-page":"75","article-title":"The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies","volume":"75","author":"Nicolson","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1111\/ane.12698-BIB0011|ane12698-cit-0011","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1136\/jnnp-2011-301999","article-title":"lamotrigine compared with levetiracetam in the initial 26 Weeks of monotherapy for focal and generalised epilepsy","volume":"83","author":"Rosenow","year":"2012","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1111\/ane.12698-BIB0012|ane12698-cit-0012","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1212\/01.wnl.0000252941.50833.4a","article-title":"Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy","volume":"68","author":"Brodie","year":"2007","journal-title":"Neurology"},{"key":"10.1111\/ane.12698-BIB0013|ane12698-cit-0013","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1111\/j.1499-1654.2000.001499.x","article-title":"Development of tolerance during chronic treatment of kindled rats with the novel antiepileptic drug levetiracetam","volume":"41","author":"Loscher","year":"2000","journal-title":"Epilepsia"},{"key":"10.1111\/ane.12698-BIB0014|ane12698-cit-0014","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1111\/j.1528-1167.2007.01516.x","article-title":"Development of tolerance to levetiracetam in rats with chronic epilepsy","volume":"49","author":"Van Vliet","year":"2008","journal-title":"Epilepsia"},{"key":"10.1111\/ane.12698-BIB0015|ane12698-cit-0015","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.seizure.2012.12.002","article-title":"Loss of the initial efficacy of levetiracetam in patients with refractory epilepsy","volume":"22","author":"Lee","year":"2013","journal-title":"Seizure"},{"key":"10.1111\/ane.12698-BIB0016|ane12698-cit-0016","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.yebeh.2008.11.016","article-title":"Validation of the Spanish version of the Liverpool Adverse Events Profile in patients with epilepsy","volume":"15","author":"Carre\u00f1o","year":"2009","journal-title":"Epilepsy Behav"},{"key":"10.1111\/ane.12698-BIB0017|ane12698-cit-0017","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.eplepsyres.2011.01.008","article-title":"Validation of the Chinese version of the Liverpool Adverse Events Profile in patients with epilepsy","volume":"94","author":"Chen","year":"2011","journal-title":"Epilepsy Res"},{"key":"10.1111\/ane.12698-BIB0018|ane12698-cit-0018","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.yebeh.2011.08.005","article-title":"Are adverse effects of antiepileptic drugs different in symptomatic partial and idiopathic generalized epilepsies? The Portuguese-Brazilian validation of the Liverpool Adverse Events Profile","volume":"22","author":"Martins","year":"2011","journal-title":"Epilepsy Behav"},{"key":"10.1111\/ane.12698-BIB0019|ane12698-cit-0019","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.yebeh.2015.03.005","article-title":"Impact of depression and anxiety on adverse event profiles in Korean people with epilepsy","volume":"46","author":"Kim","year":"2015","journal-title":"Epilepsy Behav"},{"key":"10.1111\/ane.12698-BIB0020|ane12698-cit-0020","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.yebeh.2015.11.009","article-title":"Specific adverse effects of antiepileptic drugs - A true-to-life monotherapy study","volume":"54","author":"Kowski","year":"2016","journal-title":"Epilepsy Behav"},{"key":"10.1111\/ane.12698-BIB0021|ane12698-cit-0021","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1528-1167.2006.00956.x","article-title":"The liverpool adverse events profile: relation to AED use and mood","volume":"48","author":"Panelli","year":"2007","journal-title":"Epilepsia"},{"key":"10.1111\/ane.12698-BIB0022|ane12698-cit-0022","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.seizure.2012.06.013","article-title":"Self reported adverse effects of mono and polytherapy for epilepsy","volume":"21","author":"Andrew","year":"2012","journal-title":"Seizure"},{"key":"10.1111\/ane.12698-BIB0023|ane12698-cit-0023","first-page":"CD001901","article-title":"Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review","volume":"9","author":"Mbizvo","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1111\/ane.12698-BIB0024|ane12698-cit-0024","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1528-1167.2008.01792.x","article-title":"Effects of lamotrigine compared with levetiracetam on anger, hostility, and total mood in patients with partial epilepsy","volume":"50","author":"Labiner","year":"2009","journal-title":"Epilepsia"},{"key":"10.1111\/ane.12698-BIB0025|ane12698-cit-0025","doi-asserted-by":"crossref","first-page":"e002564.","DOI":"10.1136\/bmjopen-2013-002564","article-title":"Self-reported feelings of anger and aggression towards others in patients on levetiracetam: data from the UK antiepileptic drug register","volume":"19","author":"Wieshmann","year":"2013","journal-title":"BMJ Open."},{"key":"10.1111\/ane.12698-BIB0026|ane12698-cit-0026","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0140-6736(07)60460-7","article-title":"The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial","volume":"369","author":"Marson","year":"2007","journal-title":"Lancet"}],"container-title":["Acta Neurologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.12698","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.12698","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ane.12698\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:49:52Z","timestamp":1671540592000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ane.12698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,18]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,5]]}},"URL":"https:\/\/doi.org\/10.1111\/ane.12698","archive":["Portico"],"relation":{},"ISSN":["0001-6314"],"issn-type":[{"value":"0001-6314","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10,18]]}}}