{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:45:03Z","timestamp":1769845503082,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T00:00:00Z","timestamp":1499212800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T00:00:00Z","timestamp":1499212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100015661","name":"UCB Pharma","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100015661","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neurol Scand"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1111\/ane.12794","type":"journal-article","created":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T08:06:41Z","timestamp":1499242001000},"page":"715-720","source":"Crossref","is-referenced-by-count":14,"title":["The cost-utility of sodium oxybate as narcolepsy treatment"],"prefix":"10.1155","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1682-295X","authenticated-orcid":false,"given":"K.","family":"Bolin","sequence":"first","affiliation":[{"name":"Centre for Health Economics; Department of Economics; Gothenburg University; Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Berling","sequence":"additional","affiliation":[{"name":"UCB Pharma; Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Wasling","sequence":"additional","affiliation":[{"name":"Sahlgrenska Academy; University of Gothenburg; Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Meinild","sequence":"additional","affiliation":[{"name":"UCB Pharma; Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kjellberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience and Rehabilitation; Institute of Neuroscience and Physiology; KORA; Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Jennum","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurophysiology; Faculty of Health Sciences; Danish Center for Sleep Medicine; Center for Healthy Aging; Glostrup Hospital; University of Copenhagen; Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,5]]},"reference":[{"key":"10.1111\/ane.12794-BIB0001|ane12794-cit-0001","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.sleep.2013.03.002","article-title":"Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population","volume":"14","author":"Ohayon","year":"2013","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0002|ane12794-cit-0002","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S1389-9457(01)00067-3","article-title":"The impact of narcolepsy on psychological health and role behaviours: negative effects and comparisons with other illness groups","volume":"2","author":"Bruck","year":"2001","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0003|ane12794-cit-0003","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S1474-4422(14)70075-4","article-title":"Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination","volume":"13","author":"Partinen","year":"2014","journal-title":"Lancet Neurol"},{"issue":"Suppl.","key":"10.1111\/ane.12794-BIB0004|ane12794-cit-0004","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1093\/sleep\/17.suppl_8.S45","article-title":"Psychosocial impact of narcolepsy","volume":"8","author":"Broughton","year":"1994","journal-title":"Sleep"},{"key":"10.1111\/ane.12794-BIB0005|ane12794-cit-0005","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/sleep\/9.1.200","article-title":"All-day performance variations in normal and narcoleptic subjects","volume":"9","author":"Godbout","year":"1986","journal-title":"Sleep"},{"key":"10.1111\/ane.12794-BIB0006|ane12794-cit-0006","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1046\/j.1365-2869.2001.00234.x","article-title":"Health-related quality of life in narcolepsy","volume":"10","author":"Daniels","year":"2001","journal-title":"J Sleep Res"},{"issue":"Suppl. 1","key":"10.1111\/ane.12794-BIB0007|ane12794-cit-0007","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1212\/WNL.50.2_Suppl_1.S31","article-title":"The influence of clinical symptoms on quality of life in patients with narcolepsy","volume":"50","author":"Goswami","year":"1998","journal-title":"Neurology"},{"key":"10.1111\/ane.12794-BIB0008|ane12794-cit-0008","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.sleep.2010.07.008","article-title":"A 5-year prospective cohort study on health-related quality of life in patients with narcolepsy","volume":"12","author":"Vignatelli","year":"2011","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0009|ane12794-cit-0009","doi-asserted-by":"crossref","first-page":"e0122478","DOI":"10.1371\/journal.pone.0122478","article-title":"Health-related stigma as a determinant of functioning in young adults with narcolepsy","volume":"10","author":"Kapella","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1111\/ane.12794-BIB0010|ane12794-cit-0010","doi-asserted-by":"crossref","first-page":"401","DOI":"10.5664\/jcsm.5594","article-title":"The humanistic and economic burden of narcolepsy","volume":"12","author":"Flores","year":"2016","journal-title":"J Clin Sleep Med"},{"key":"10.1111\/ane.12794-BIB0011|ane12794-cit-0011","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.sleep.2012.08.002","article-title":"The burden of narcolepsy with cataplexy: how disease history and clinical features influence socio-economic outcomes","volume":"13","author":"Ingravallo","year":"2012","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0012|ane12794-cit-0012","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000367653","article-title":"Health, social and economic consequences of polyneuropathy: a controlled national study evaluating societal effects on patients and their partners","volume":"73","author":"Jennum","year":"2015","journal-title":"Eur Neurol"},{"key":"10.1111\/ane.12794-BIB0013|ane12794-cit-0013","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s10198-013-0491-2","article-title":"Health, social and economic consequences of hypersomnia: a controlled national study from a national registry evaluating the societal effect on patients and their partners","volume":"15","author":"Jennum","year":"2014","journal-title":"Eur J Health Econ"},{"key":"10.1111\/ane.12794-BIB0014|ane12794-cit-0014","doi-asserted-by":"crossref","first-page":"835","DOI":"10.5665\/sleep.2706","article-title":"Comorbidity and mortality of narcolepsy: a controlled retro- and prospective national study","volume":"2013","author":"Jennum","year":"2013","journal-title":"Sleep"},{"key":"10.1111\/ane.12794-BIB0015|ane12794-cit-0015","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.sleep.2012.06.006","article-title":"Health, social, and economic consequences of narcolepsy: a controlled national study evaluating the societal effect on patients and their partners","volume":"8","author":"Jennum","year":"2012","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0016|ane12794-cit-0016","first-page":"19","article-title":"L\u00e4kemedelsbehandling av narkolepsi - bakgrundsdokumentation","volume":"24","author":"L\u00e4kemedelsverket 2013","year":"2013","journal-title":"Inform L\u00e4kemedelsverket"},{"key":"10.1111\/ane.12794-BIB0017|ane12794-cit-0017","first-page":"21","article-title":"L\u00e4kemedelsbehandling av narkolepsi - ett kunskapsdokument","volume":"24","author":"L\u00e4kemedelsverket 2013","year":"2013","journal-title":"Inform L\u00e4kemedelsverket"},{"key":"10.1111\/ane.12794-BIB0018|ane12794-cit-0018","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s40263-016-0337-4","article-title":"Treatment options for narcolepsy","volume":"30","author":"Barateau","year":"2016","journal-title":"CNS Drugs"},{"key":"10.1111\/ane.12794-BIB0019|ane12794-cit-0019","first-page":"42","article-title":"A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy","volume":"25","author":"The US Xyrem\u00ae Multicenter Study Group","year":"2002","journal-title":"Sleep"},{"key":"10.1111\/ane.12794-BIB0020|ane12794-cit-0020","first-page":"31","article-title":"A 12-month, open-label, multicenter extension trial of orally administered sodium oxybate for the treatment of narcolepsy","volume":"26","author":"The US Xyrem\u00ae Multicenter Study Group","year":"2003","journal-title":"Sleep"},{"key":"10.1111\/ane.12794-BIB0021|ane12794-cit-0021","doi-asserted-by":"crossref","first-page":"391","DOI":"10.5664\/jcsm.26368","article-title":"A double-blind, placebo-controlled study demonstrates sodium oxybate is effective for the treatment of excessive daytime sleepiness in narcolepsy","volume":"1","author":"The Xyrem\u00ae International Study Group","year":"2005","journal-title":"J Clin Sleep Med"},{"key":"10.1111\/ane.12794-BIB0022|ane12794-cit-0022","unstructured":"Hayduk R Mitler M Sodium oxybate therapy improves the quality of life of narcolepsy patients 2001 A328"},{"key":"10.1111\/ane.12794-BIB0023|ane12794-cit-0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/WNF.0b013e318203d415","article-title":"Long-term follow-up of patients with narcolepsy-cataplexy treated with sodium oxybate (xyrem)","volume":"34","author":"Alshaikh","year":"2011","journal-title":"Clin Neuropharmacol"},{"key":"10.1111\/ane.12794-BIB0024|ane12794-cit-0024","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.smrv.2011.09.001","article-title":"Narcolepsy and effectiveness of gamma-hydroxybutyrate (GHB): a systematic review and meta-analysis of randomized controlled trials","volume":"16","author":"Boscolo-Bertoa","year":"2012","journal-title":"Sleep Med Rev"},{"key":"10.1111\/ane.12794-BIB0025|ane12794-cit-0025","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.sleep.2014.10.004","article-title":"A 12-week open-label, multicenter study evaluating the safety and patient-reported efficacy of sodium oxybate in patients with narcolepsy and cataplexy","volume":"16","author":"Mamelak","year":"2015","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0026|ane12794-cit-0026","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.sleep.2015.10.005","article-title":"Benefits and risk of sodium oxybate in idiopathic hypersomnia versus narcolepsy type 1: a chart review","volume":"17","author":"Leu-Semenescu","year":"2016","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0027|ane12794-cit-0027","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1111\/jsr.12386","article-title":"Improved vigilance after sodium oxybate treatment in narcolepsy: a comparison between in-field and in-laboratory measurements","volume":"25","author":"Schie","year":"2016","journal-title":"J Sleep Res"},{"key":"10.1111\/ane.12794-BIB0028|ane12794-cit-0028","unstructured":"European Medicines Evaluation Agency (EMEA) 2007 Scientific discussion of the European Public Assessment report for Xyrem"},{"key":"10.1111\/ane.12794-BIB0029|ane12794-cit-0029","first-page":"161","article-title":"Sodium oxybate for narcolepsy with cataplexy-A cost-effective analysis","volume":"5","author":"Lanting","year":"2014","journal-title":"J Neuroinfect Dis"},{"key":"10.1111\/ane.12794-BIB0030|ane12794-cit-0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jval.2015.09.2465","article-title":"Cost effectiveness of sodium oxybate in treatment of cataplexy in patients with narcolepy in turkey","volume":"18","author":"Tatar","year":"2015","journal-title":"Value Health"},{"key":"10.1111\/ane.12794-BIB0031|ane12794-cit-0031","volume-title":"Methods for the economic evaluation of health care programmes","author":"Drummond","year":"2015"},{"key":"10.1111\/ane.12794-BIB0032|ane12794-cit-0032","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0167-6296(01)00130-8","article-title":"The estimation of a preference-based measure of health from the SF-36","volume":"21","author":"Brazier","year":"2001","journal-title":"J Health Econ"},{"key":"10.1111\/ane.12794-BIB0033|ane12794-cit-0033","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.sleep.2016.09.013","article-title":"Morbidity of childhood onset narcolepsy: a controlled national study","volume":"29","author":"Jennum","year":"2017","journal-title":"Sleep Med"},{"key":"10.1111\/ane.12794-BIB0034|ane12794-cit-0034","volume-title":"Diagnosis-Related Groups in Europe - Moving Towards Transparency Efficiency and Quality in Hospitals","author":"Linna","year":"2011"},{"key":"10.1111\/ane.12794-BIB0035|ane12794-cit-0035","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1111\/j.1468-1331.2006.01473.x","article-title":"EFNS guidelines on management of narcolepsy","volume":"13","author":"Billiard","year":"2006","journal-title":"Eur J Neurol"}],"container-title":["Acta Neurologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.12794","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ane.12794\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:50:34Z","timestamp":1671540634000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ane.12794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,5]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"URL":"https:\/\/doi.org\/10.1111\/ane.12794","archive":["Portico"],"relation":{},"ISSN":["0001-6314"],"issn-type":[{"value":"0001-6314","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7,5]]}}}