{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T06:59:25Z","timestamp":1763535565359,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T00:00:00Z","timestamp":1538956800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T00:00:00Z","timestamp":1538956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Beverly and James Peters and Linda and Robert Brill"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Neurol Scand"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1111\/ane.13027","type":"journal-article","created":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T10:27:16Z","timestamp":1537093636000},"page":"82-85","source":"Crossref","is-referenced-by-count":20,"title":["MELAS: Monitoring treatment with magnetic resonance spectroscopy"],"prefix":"10.1155","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3099-9129","authenticated-orcid":false,"given":"Dominic A.","family":"Hovsepian","sequence":"first","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Galati","sequence":"additional","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Chong","sequence":"additional","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajarshi","family":"Mazumder","sequence":"additional","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"DeGiorgio","sequence":"additional","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"},{"name":"LAC Olive View; UCLA Medical Center; Sylmar California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shri","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Neurology; David Geffen; UCLA School of Medicine; Los Angeles California"},{"name":"LAC Olive View; UCLA Medical Center; Sylmar California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Yim","sequence":"additional","affiliation":[{"name":"LAC Olive View; UCLA Medical Center; Sylmar California"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,8]]},"reference":[{"issue":"1-2","key":"10.1111\/ane.13027-BIB0001|ane13027-cit-0001","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ymgme.2015.06.004","article-title":"MELAS syndrome: clinical manifestations, pathogenesis, and treatment options","volume":"116","author":"El-Hattab","year":"2015","journal-title":"Mol Genet Metab"},{"issue":"8","key":"10.1111\/ane.13027-BIB0002|ane13027-cit-0002","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1007\/s00415-016-8069-4","article-title":"L-Arginine intervention at hyper-acute phase protects the prolonged MRI abnormality in MELAS","volume":"263","author":"Kitamura","year":"2016","journal-title":"J Neurol"},{"issue":"7","key":"10.1111\/ane.13027-BIB0003|ane13027-cit-0003","doi-asserted-by":"crossref","first-page":"481-483","DOI":"10.1016\/j.braindev.2004.01.006","article-title":"Beneficial effect of L-arginine for stroke-like episode in MELAS","volume":"26","author":"Kubota","year":"2004","journal-title":"Brain Dev"},{"issue":"2","key":"10.1111\/ane.13027-BIB0004|ane13027-cit-0004","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1212\/WNL.0000000000001726","article-title":"Clinical and radiologic reversal of stroke-like episodes in MELAS with high-dose L-arginine","volume":"85","author":"Siddiq","year":"2015","journal-title":"Neurology"},{"issue":"1-2","key":"10.1111\/ane.13027-BIB0005|ane13027-cit-0005","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.mito.2006.11.006","article-title":"MELAS and L-arginine therapy","volume":"7","author":"Koga","year":"2007","journal-title":"Mitochondrion"},{"issue":"5","key":"10.1111\/ane.13027-BIB0006|ane13027-cit-0006","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1001\/jamaneurol.2015.5072","article-title":"Recommendations for the management of strokelike episodes in patients with mitochondrial encephalomyopathy, lactic acidosis and strokelike episodes","volume":"73","author":"Koenig","year":"2016","journal-title":"JAMA Neurol"},{"issue":"7905","key":"10.1111\/ane.13027-BIB0007|ane13027-cit-0007","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0140-6736(75)92830-5","article-title":"Assessment of outcome after severe brain damage","volume":"1","author":"Jennett","year":"1975","journal-title":"Lancet"},{"issue":"5","key":"10.1111\/ane.13027-BIB0008|ane13027-cit-0008","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1161\/01.STR.19.5.604","article-title":"Interobserver agreement for the assessment of handicap in stroke patients","volume":"19","author":"Swieten","year":"1988","journal-title":"Stroke"},{"issue":"8","key":"10.1111\/ane.13027-BIB0009|ane13027-cit-0009","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1212\/01.WNL.0000120557.83907.A8","article-title":"Cerebral lactic acidosis correlates with neurological impairment in MELAS","volume":"62","author":"Kaufmann","year":"2004","journal-title":"Neurology"},{"issue":"2","key":"10.1111\/ane.13027-BIB0010|ane13027-cit-0010","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.braindev.2008.12.003","article-title":"Pathophysiologic evaluation of MELAS strokes by serially quantified MRS and CASL perfusion images","volume":"32","author":"Tsujikawa","year":"2010","journal-title":"Brain Dev"},{"issue":"5","key":"10.1111\/ane.13027-BIB0011|ane13027-cit-0011","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/mrm.1910340511","article-title":"Reversible decreases in N-acetylaspartate after acute brain injury","volume":"34","author":"De Stefano","year":"1995","journal-title":"Magn Reson Med"},{"issue":"6","key":"10.1111\/ane.13027-BIB0012|ane13027-cit-0012","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1001\/archneur.55.6.849","article-title":"Magnetic resonance spectroscopy: use in monitoring MELAS treatment","volume":"55","author":"Pavlakis","year":"1998","journal-title":"Arch Neurol"},{"key":"10.1111\/ane.13027-BIB0013|ane13027-cit-0013","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jns.2004.11.014","article-title":"Magnetic resonance spectroscopy in patients with MELAS","volume":"229-230","author":"Moller","year":"2005","journal-title":"J Neurol Sci"}],"container-title":["Acta Neurologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fane.13027","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ane.13027\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:51:43Z","timestamp":1671540703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ane.13027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,8]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"URL":"https:\/\/doi.org\/10.1111\/ane.13027","archive":["Portico"],"relation":{},"ISSN":["0001-6314"],"issn-type":[{"type":"print","value":"0001-6314"}],"subject":[],"published":{"date-parts":[[2018,10,8]]}}}