{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:47:50Z","timestamp":1791161270131,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The 2009 \u201cAHA\/ACCF\/HRS Recommendations for Standardization and Interpretation of the Electrocardiogram\u201d state that left ventricular hypertrophy (LVH) criteria that include R\u2010wave amplitude in leads I and aVL are not likely reliable in the presence of left anterior fascicular block (LAFB). This statement was referenced to three relatively small studies. The present study reexamines the utility of selected electrocardiographic (ECG) criteria for LVH in the presence of LAFB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified 185 ECG tracings with LAFB from patients in whom echocardiogram had been performed within 30 days of the ECG. These ECGs were evaluated for the presence of selected LVH criteria: (1) Sokolow index (R\u2010wave\u2010aVL &gt; 11 mm); (2) Cornell criteria (R\u2010wave\u2010aVL + S\u2010wave\u2010V3 &gt; 28 mm in men (&gt;20 mm in women); (3) Gertsch criterion (S\u2010wave\u2010III + (R + S) maximal precordial &gt;30 mm); and (4) Bozzi criterion (SV1 or SV2 + (RV6 + SV6) &gt; 25 mm). The \u201cgold standard\u201d for LVH was left ventricular mass index on echocardiogram.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Although the aVL\u2010based LVH criteria demonstrated lower sensitivity (45\u201368%) and a trend toward higher specificity (67\u201381%) compared to non\u2010aVL\u2010based criteria, the four studied criteria demonstrated similar diagnostic accuracy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the presence of LAFB, the aVL\u2010based Sokolow index and Cornell criteria, which were excluded from 2009 multisociety ECG guidelines, identify LVH with similar diagnostic accuracy as the non\u2010aVL\u2010based criteria that were included. Moreover, they are easier to calculate and are included in some of the computer\u2010assisted ECG interpretation software presently in use. Their exclusion from the 2009 guidelines was unnecessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12029","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T02:03:07Z","timestamp":1359079387000},"page":"21-28","source":"Crossref","is-referenced-by-count":8,"title":["Diagnosis of Left Ventricular Hypertrophy in the Presence of Left Anterior Fascicular Block: A Reexamination of the 2009 AHA\/ACCF\/HRS Guidelines"],"prefix":"10.1111","volume":"18","author":[{"given":"Sandeep","family":"Ravi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Bridgeport Hospital Yale University  Bridgeport CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir","family":"Rukshin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bridgeport Hospital Yale University  Bridgeport CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilead","family":"Lancaster","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bridgeport Hospital Yale University  Bridgeport CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Zarich","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bridgeport Hospital Yale University  Bridgeport CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"McPherson","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bridgeport Hospital Yale University  Bridgeport CT"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-114-5-345"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-005-1893-1"},{"key":"e_1_2_10_4_1","first-page":"156","article-title":"Left ventricular hypertrophy resulting from systemic hypertension: Adaptive advantage and adverse consequences","volume":"2","author":"Taylor AL","year":"1991","journal-title":"J Assoc Acad Minor Phys"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.015"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.12.013"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000398448","article-title":"Left anterior hemiblock and electrocardiographic diagnosis of left ventricular hypertrophy","volume":"16","author":"Bozzi G","year":"1976","journal-title":"Adv Cardiol"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90133-6"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(92)90080-M"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2001.tb00129.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(85)80115-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03625.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.67.4.907"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(84)80433-7"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3"},{"key":"e_1_2_10_16_1","first-page":"554","article-title":"Is electrocardiographic diagnosis of left ventricular hypertrophy possible in the presence of an anterior hemiblock?","volume":"122","author":"Schlapfer J","year":"1992","journal-title":"Schweiz Med Wochenschr"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470317082"}],"container-title":["Annals of Noninvasive Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fanec.12029","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anec.12029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T17:16:10Z","timestamp":1697476570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/anec.12029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/anec.12029"],"URL":"https:\/\/doi.org\/10.1111\/anec.12029","archive":["Portico"],"relation":{},"ISSN":["1082-720X","1542-474X"],"issn-type":[{"value":"1082-720X","type":"print"},{"value":"1542-474X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}