{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T04:31:07Z","timestamp":1782189067581,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T00:00:00Z","timestamp":1364256000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Although carotid stenting is an effective treatment for severe carotid stenosis, it has been associated with alterations in autonomic functions during or shortly after the procedure. Heart rate variability (HRV) is an established tool for the asessment of autonumic functions. In this study, our aim was to investigate the relation between the alterations in autonomic functions and HRV by Holter monitoring parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients (19 male, 8 female) that are suitable for carotid artery stenting, without a history of hypertension, diabetes mellitus, severe coronary artery or valvular heart disease, were enrolled to our study. Short\u2010term HRV analysis recordings were obtained at the beginning, and after the procedure. The square root of the mean squared differences of successive NN intervals (RMSSD), total frequency, low frequency (LF), high frequency (HF), normalized units LF (LFnu), normalized units HF (HFnu), LF\/HF ratios were analyzed. Results were statistically analysed by using Wilcoxon test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total frequency did not show any significant changes after the procedure (1101 \u00b1 829, 981 \u00b1 855). While RMSSD and HFnu values significantly increased respectively (23 \u00b1 12\/33 \u00b1 22, and 22 \u00b1 10\/35 \u00b1 10, p &lt; 0.05) after the procedure, HF values increased nonsignificantly after the procedure (82 \u00b1 92\/92 \u00b1 108). LF, LFnu, and LF\/HF values were significantly decreased after the procedure. (228 \u00b1 166\/112 \u00b1 100, 70 \u00b1 15\/55 \u00b1 18, 4 \u00b1 2.5\/2.1 \u00b1 2, respectively, p &lt; 0.05)<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While RMSSD and HF are used as markers of vagal activity, LF is a marker of sympathetic modulation and LF\/HF ratio shows sympathovagal balance. In our study, we showed that carotid artery stenting is associated with increase in parasympathetic activation, and this finding is demonstrated by HRV parameters.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12054","type":"journal-article","created":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T04:02:30Z","timestamp":1364356950000},"page":"126-129","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of Autonomic Functions by Heart Rate Variability after Stenting in Patients with Carotid Artery Stenosis"],"prefix":"10.1111","volume":"18","author":[{"given":"Gokhan","family":"Alici","sequence":"first","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birol","family":"Ozkan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goksel","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muslum","family":"Sahin","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Vefik","family":"Yazicioglu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Bulut","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman Gazi","family":"Kiraz","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Metin","family":"Esen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Kartal Kosuyolu Yuksek Ihtisas Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526.38.4.281"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.215.3.r00jn04677"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.08.079"},{"key":"e_1_2_6_5_1","first-page":"1043","article-title":"Heart rate variability: Standards of measurement, physiological \u0131nterpretation, and clinical use","volume":"93","year":"1996","journal-title":"Task Force 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