{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:52:41Z","timestamp":1784130761293,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,11,8]],"date-time":"2013-11-08T00:00:00Z","timestamp":1383868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Low vitamin D status has been associated with increased risk of cardiovascular disease. Atrial fibrillation (AF) is the most common cardiac arrhythmia. We evaluated the association between low vitamin D and AF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed data from 162 Chinese patients with nonvalvular persistent AF and no other cardiovascular disease whose serum 25\u2010hydroxyvitamin D [25(OH)D] levels were measured in our hospital (AF group). Healthy subjects without AF who underwent health screening at our hospital served as controls (non\u2010AF group, n = 160). 25(OH)D was measured by chemiluminescence assay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The serum 25(OH)D level was significantly lower in the AF group than in the non\u2010AF group (18.5 \u00b1 10.3 vs 21.4 \u00b1 10.7 ng\/mL, P &lt; 0.05). The high\u2010sensitivity C\u2010reactive protein (hsCRP) level was significantly higher in the AF group than in the non\u2010AF group (0.35 \u00b1 0.19 vs 0.2 \u00b1 0.17 mg\/dL, P &lt; 0.01). The average left atrial diameter was significantly larger in the AF group than in the non\u2010AF group (P &lt; 0.01). The serum 25(OH)D level showed a negative correlation with left atrial diameter, hsCRP level, and pulmonary artery systolic pressure. Logistic regression analysis identified that 25(OH)D was related to AF. Patients whose vitamin D levels were in the lowest 25(OH)D category (&lt;20 ng\/mL) were more often in the AF group, with their incidence about twofold higher than those in the highest 25(OH)D category (&gt;30 ng\/mL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Low vitamin D levels are associated with AF. It may be involved in its development.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12105","type":"journal-article","created":{"date-parts":[[2013,11,8]],"date-time":"2013-11-08T10:07:39Z","timestamp":1383905259000},"page":"166-173","source":"Crossref","is-referenced-by-count":50,"title":["Relation of Low Vitamin D to Nonvalvular Persistent Atrial Fibrillation in Chinese Patients"],"prefix":"10.1111","volume":"19","author":[{"given":"Wei Ren","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Cardiology South\u2010Building, PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology South\u2010Building, PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Cardiology South\u2010Building, PLA General 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