{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:42:14Z","timestamp":1772890934542,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T00:00:00Z","timestamp":1484524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Low\u2010voltage areas (<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s) are frequently observed in patients with persistent atrial fibrillation (Pe<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) and may represent adverse atrial remodeling. However, noninvasive method of evaluating <jats:styled-content style=\"fixed-case\">LAV<\/jats:styled-content>s is not well established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a cohort of 68 patients with Pe<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>, endocardial voltage maps of left atrium (<jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>) were created during sinus rhythm after pulmonary vein isolation (<jats:styled-content style=\"fixed-case\">PVI<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s were defined as areas with electrogram amplitudes &lt;0.5 <jats:styled-content style=\"fixed-case\">mV<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s were correlated with clinical, echocardiographic, surface, and transesophageal electrocardiography (<jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content>) variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content> voltage mapping revealed any degree of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s in 50 (73.5%) patients. Patients with <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s were older, had a longer history of <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>, and lower fibrillatory wave (F wave) amplitude on <jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> (0.27\u00a0\u00b1\u00a00.06 vs 0.39\u00a0\u00b1\u00a00.08 mv, <jats:italic>p\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.01) as compared to patients without <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s. The extent of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s was weakly correlated with age (<jats:italic>R\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.36, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.03) and <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> duration (<jats:italic>R\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.26, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.02), but significantly correlated with F\u2010wave amplitude on <jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> (<jats:italic>R\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>\u22120.57, <jats:italic>p\u00a0&lt;\u00a0<\/jats:italic>.01). Only F\u2010wave amplitude on <jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> was found as independent predictor for the presence of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a01.53, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\u00a0=\u00a01.09\u20132.96, <jats:italic>p\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.03). A receiver operating characteristic (<jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>) curve identified an F\u2010wave amplitude of 0.29 <jats:styled-content style=\"fixed-case\">mV<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>\u00a0=\u00a00.788; sensitivity\u00a0=\u00a068.4%; specificity\u00a0=\u00a073.2%) on <jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> as the optimal cutoff value for predicting <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As a noninvasive investigation, F\u2010wave amplitude on <jats:styled-content style=\"fixed-case\">TE<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">ECG<\/jats:styled-content> may be used as an indicator for the presence of <jats:styled-content style=\"fixed-case\">LA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">LVA<\/jats:styled-content>s.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12421","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T05:06:39Z","timestamp":1484543199000},"source":"Crossref","is-referenced-by-count":11,"title":["Fibrillatory wave amplitude on transesophageal <scp>ECG<\/scp> as a marker of left atrial low\u2010voltage areas in patients with persistent atrial fibrillation"],"prefix":"10.1111","volume":"22","author":[{"given":"Ran","family":"Yin","sequence":"first","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongnan","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongming","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jintian","family":"Pen","sequence":"additional","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeqi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Caridiology The First Affiliated Hospital of Nanchang University  Nanchang City 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