{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:52:58Z","timestamp":1774536778831,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Swedish National Health Service"},{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"Background<\/jats:title>Myocardial scar burden quantification is an emerging clinical parameter for risk stratification of sudden cardiac death and prediction of ventricular arrhythmias in patients with left ventricular dysfunction. We investigated the relationships among semiautomated Selvester score burden and late gadolinium enhancement\u2010cardiovascular magnetic resonance (LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content>) assessed scar burden and clinical outcome in patients with underlying heart failure, left bundle branch block (LBBB<\/jats:styled-content>) and implantable cardioverter\u2010defibrillator (ICD<\/jats:styled-content>) treatment.<\/jats:p><\/jats:sec>Methods<\/jats:title>Selvester QRS<\/jats:styled-content> scoring was performed on all subjects with ischemic and nonischemic dilated cardiomyopathy at Sk\u00e5ne University Hospital Lund (2002\u20132013) who had undergone LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content> and 12\u2010lead ECG<\/jats:styled-content> with strict LBBB<\/jats:styled-content> pre\u2010ICD<\/jats:styled-content> implantation.<\/jats:p><\/jats:sec>Results<\/jats:title>Sixty patients were included; 57% nonischemic dilated cardiomyopathy and 43% ischemic cardiomyopathy with mean left ventricular ejection fraction of 27.6%\u00a0\u00b1\u00a011.7. All patients had scar by Selvester scoring. Sixty\u2010two percent had scar by LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content> (n<\/jats:italic>\u00a0=\u00a037). The Spearman correlation coefficient for LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content> and Selvester score derived scar was r<\/jats:italic>\u00a0=\u00a0.35 (p<\/jats:italic>\u00a0=\u00a0.007). In scar negative LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content>, there was evidence of scar by Selvester scoring in all patients (range 3%\u201333%, median 15%). Fourteen patients (23%) had an event during the follow\u2010up period; 11 (18%) deaths and six adequate therapies (10%). There was a moderate trend indicating that presence of scar increased the risk of clinical endpoints in the LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content> analysis (p<\/jats:italic>\u00a0=\u00a0.045).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>There is a modest correlation between LGE<\/jats:styled-content>\u2010CMR<\/jats:styled-content> and Selvester scoring verified myocardial scar. CMR<\/jats:styled-content> based scar burden is correlated to clinical outcome, but Selvester scoring is not. The Selvester scoring algorithm needs to be further refined in order to be clinically relevant and reliable for detailed scar evaluation in patients with LBBB<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12440","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T11:12:59Z","timestamp":1488366779000},"source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of the ECG<\/scp> based Selvester scoring method to estimate myocardial scar burden and predict clinical outcome in patients with left bundle branch block, with comparison to late gadolinium enhancement CMR<\/scp> imaging"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5186-0252","authenticated-orcid":false,"given":"Uzma","family":"Chaudhry","sequence":"first","affiliation":[{"name":"Arrhythmia Clinic Sk\u00e5ne University Hospital Lund Sweden"},{"name":"Department of Cardiology, Clinical Sciences Lund University Lund 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University Hospital and Lund University Lund Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiajuang","family":"Xia","sequence":"additional","affiliation":[{"name":"Heart Research Follow\u2010Up Program University of Rochester Rochester NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Wieslander","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology Karolinska Institutet, and Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brett D.","family":"Atwater","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Strauss","sequence":"additional","affiliation":[{"name":"Office of Science and Engineering Laboratories Center for Devices and Radiological Health US Food and Drug Administration Silver Spring MD 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