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Underlying molecular, cellular, and interstitial changes manifest clinically as changes in size, mass, geometry, and function of the heart. Cardiac remodeling is associated with progressive ventricular dysfunction, arrhythmias, and impaired prognosis. Clinical and diagnostic notions about LBBB have evolved from a simple electrocardiographic alteration to a critically important finding affecting diagnostic and clinical management of many patients. Advances in cardiac magnetic resonance imaging have significantly improved the assessment of patients with LBBB and provided additional insights into pathophysiological mechanisms of left ventricular remodeling. In this review, we will discuss the epidemiology, etiologies, and electrovectorcardiographic features of LBBB and propose a classification of the conduction disturbance.<\/jats:p>","DOI":"10.1111\/anec.12572","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T11:46:11Z","timestamp":1529667971000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Left bundle branch block: Epidemiology, etiology, anatomic features, electrovectorcardiography, and classification proposal"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4948-538X","authenticated-orcid":false,"given":"Andr\u00e9s R.","family":"P\u00e9rez\u2010Riera","sequence":"first","affiliation":[{"name":"Design of Studies and Scientific Writing Laboratory ABC School of Medicine S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimundo","family":"Barbosa\u2010Barros","sequence":"additional","affiliation":[{"name":"Coronary Center Messejana Hospital Dr. Carlos Alberto Studart Gomes Fortaleza, Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2468-3953","authenticated-orcid":false,"given":"Marianne P. 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