{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T02:39:06Z","timestamp":1768012746304,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T00:00:00Z","timestamp":1534464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Fragmented QRS (fQRS) complex is an electrocardiographic pattern that reflects the inhomogeneity of ventricular depolarization. The aims of this study were to determine the prognostic significance of fQRS for predicting in\u2010hospital life\u2010threatening arrhythmic complications in ST\u2010elevation myocardial infarction (STEMI) patients, and to identify the most appropriate duration of cardiac rhythm monitoring in STEMI patients with fQRS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients diagnosed with and treated for STEMI at Siriraj Hospital (Bangkok, Thailand) during 2009\u20132012 were enrolled. Patients were divided according to fQRS status (having or not having fQRS) at hospital admission. The primary outcome was in\u2010hospital life\u2010threatening arrhythmic events, including sustained ventricular tachycardia and ventricular fibrillation. Time to last life\u2010threatening arrhythmic event from hospital admission was recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 452 patients that were included, 96 patients (21.2%) had fQRS. There were significantly more life\u2010threatening arrhythmic events in the fQRS group than in the non\u2010fQRS group (22.9% vs. 4.5%, respectively; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Median (IQR) time to last life\u2010threatening arrhythmic event from hospital admission was significantly longer in fQRS than in non\u2010fQRS (6.58\u00a0hr [3.08\u201339.34] vs. 2.59\u00a0hr [1.75\u20135.75], respectively; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.047). Multivariate analysis identified fQRS as an independent predictor of in\u2010hospital life\u2010threatening arrhythmic events (OR: 4.162, 95% CI: 1.669\u201310.384; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of fQRS complex on admission ECG was found to be an independent predictor of in\u2010hospital life\u2010threatening arrhythmic events in STEMI patients. Since the time to last life\u2010threatening arrhythmic event from admission was longer in fQRS than in non\u2010fQRS, cardiac rhythm monitoring longer than 24\u201348\u00a0hr may be needed in patients with fQRS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12593","type":"journal-article","created":{"date-parts":[[2018,8,17]],"date-time":"2018-08-17T10:48:30Z","timestamp":1534502910000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Fragmented QRS as a predictor of in\u2010hospital life\u2010threatening arrhythmic complications in ST\u2010elevation myocardial infarction patients"],"prefix":"10.1111","volume":"24","author":[{"given":"Tanawat","family":"Attachaipanich","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8684-2361","authenticated-orcid":false,"given":"Rungroj","family":"Krittayaphong","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.12.057"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.595892"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2009.09.065"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.07.046"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2007.06.024"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.39.4.531"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38985.646481.55"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.72.3.596"},{"issue":"2","key":"e_1_2_8_10_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","article-title":"2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST\u2010segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST\u2010segment elevation of the European Society of Cardiology (ESC)","volume":"39","author":"Ibanez B.","year":"2017","journal-title":"European Heart Journal"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2009.11.006"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2013.11.026"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2013.05.005"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nuclcard.2007.02.003"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.600"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2007.05.003"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.770917"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2008.00867.x"},{"issue":"4","key":"e_1_2_8_19_1","first-page":"E362","article-title":"2013 ACCF\/AHA guideline for the management of ST\u2010elevation myocardial infarction a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"127","author":"O'Gara P. 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