{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:10Z","timestamp":1787013850208,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the efficacy and safety of left bundle branch area pacing (LBBaP) in patients with heart failure and left bundle branch block (LBBB), and to compare the clinical effects with traditional cardiac resynchronization therapy (CRT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010two patients with dilated cardiomyopathy complicated by cardiac insufficiency and left bundle branch block were divided into CRT group and LBBaP group. Parameters including pacing threshold, R\u2010wave amplitude, pacing impedance and operation time, and X\u2010ray exposure time were recorded. The left ventricular ejection fraction (LVEF), left ventricular end\u2010diastolic diameter (LVEDD), and left ventricular end\u2010systolic diameter (LVESD) were examined by echocardiography. The changes of QRS complex before and after operation were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with CRT group, the LBBaP group spent less time on total operation time and X\u2010ray exposure time and had stable electrode parameters including pacing threshold, R\u2010wave amplitude, and lead impedance after 12\u2010month follow\u2010up. In addition, LBBaP can achieve narrow QRS complex (117.15\u00a0\u00b1\u00a09.91)\u00a0ms immediately than that in CRT group (130.32\u00a0\u00b1\u00a012.41)\u00a0ms. The change of QRS between LBBaP is (50.30\u00a0\u00b1\u00a023.79)\u00a0ms and CRT group is (33.15\u00a0\u00b1\u00a020.22)\u00a0ms. After 6\u00a0months' follow\u2010up in LBBaP group, EF was higher than that before operation. Followed up for 12\u00a0months after operation, EF and LVEDD in LBBaP group were significantly improved compared with those before operation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Left bundle branch area pacing is a safe and effective resynchronization method for patients with cardiac insufficiency and asynchronization, which can achieve same clinical effects to CRT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anec.12898","type":"journal-article","created":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T08:59:01Z","timestamp":1632301141000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Cardiac resynchronization performed by LBBaP\u2010CRT in patients with cardiac insufficiency and left bundle branch block"],"prefix":"10.1111","volume":"26","author":[{"given":"Linna","family":"Zu","sequence":"first","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"},{"name":"Department of Cardiology Aviation General Hospital China Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zefeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Hang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Aviation General Hospital China Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liting","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junmeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart Center the First Hospital of Tsinghua University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongquan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.048"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.073"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq038"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy252"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euy252"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.8.869"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.08.005"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.09.013"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl\u20102018\u2010313415"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.003344"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv727"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.592"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.05.005"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pace.12904"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.01.105"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.23215"}],"container-title":["Annals of Noninvasive Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anec.12898","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/anec.12898","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anec.12898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T08:02:51Z","timestamp":1693209771000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/anec.12898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,22]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/anec.12898"],"URL":"https:\/\/doi.org\/10.1111\/anec.12898","archive":["Portico"],"relation":{},"ISSN":["1082-720X","1542-474X"],"issn-type":[{"value":"1082-720X","type":"print"},{"value":"1542-474X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,22]]},"assertion":[{"value":"2021-06-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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