{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:52:38Z","timestamp":1792000358934,"version":"4.4.0"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T00:00:00Z","timestamp":1638576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["20hk0102071h0001"],"award-info":[{"award-number":["20hk0102071h0001"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K08140"],"award-info":[{"award-number":["21K08140"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Telerehabilitation is an alternative clinic\u2010based rehabilitation. A remote monitoring (RM) system attached to a cardiac rhythm device can collect physiological data and the device function. This study aimed to evaluate the safety and feasibility of telerehabilitation supervised by an RM in patients receiving cardiac resynchronization therapy (CRT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A single group pre\u2013post exercise program was implemented for 3\u00a0months in 18 CRT recipients.\u00a0The exercise regimen consisted of walking a prescribed number of steps based on a 6\u2010min walk distance (6MWD) achieved at baseline. The patients were asked to exercise 3 to 5 times per week for up to 30\u00a0min per session, wearing an accelerometer to document the number of steps taken. The safety was assessed by the heart failure hospitalizations and all\u2010cause death. The feasibility was measured by the improvement in the quality of life (QOL) using the EuroQol 5 dimensions, and daily active time measured by the CRT, 6MWD, B\u2010type natriuretic peptide (BNP) level, and left ventricular ejection fraction (LVEF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No patients had heart failure hospitalizations or died. No patients had any ventricular tachyarrhythmias. One patient needed to suspend the exercise due to signs of exacerbated heart failure by the RM. Compared to baseline, there were significant improvements in the QOL (\u22120.037, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.05), active time (1.12%\/day, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.05), and 6MWD (11\u00a0m, <jats:italic>p\u00a0<\/jats:italic>&lt;\u00a0.001), but not the BNP (\u201332.4\u00a0pg\/ml, <jats:italic>p\u00a0<\/jats:italic>=\u00a0.07) or LVEF (0.28%, <jats:italic>p\u00a0<\/jats:italic>=\u00a0.55).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Three months of RM\u2010guided walking exercise in patients with CRT significantly increased the QOL, active time, and exercise capacity without any adverse effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.12926","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T15:38:06Z","timestamp":1638632286000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Safety and feasibility of a telemonitoring\u2010guided exercise program in patients receiving cardiac resynchronization therapy"],"prefix":"10.1111","volume":"27","author":[{"given":"Asami","family":"Koike","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Sobue","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Fujita Health University Bantane Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayumi","family":"Kawai","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fujita Health University School of Medicine  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukina","family":"Banno","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Fujita Health University Hospital  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mashide","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of Cardiology Fujita Health University School of Medicine  Toyoake Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Kiyono","sequence":"additional","affiliation":[{"name":"Division of Bioengineering Graduate School of Engineering Science Osaka University  Toyonaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2375-2323","authenticated-orcid":false,"given":"Eiichi","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Fujita Health University Bantane Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.184461"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjr.0000230104.93771.7d"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2016.12.011"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJR.0b013e32801164b3"},{"issue":"3","key":"e_1_2_11_6_1","first-page":"307","article-title":"The effects of training on heart rate; A longitudinal study","volume":"35","author":"Karvonen M. 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