{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:24:10Z","timestamp":1753878250368,"version":"3.41.2"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Coronary artery tortuosity (CAT) is frequently detected during coronary angiography or coronary electron\u2010beam computed tomography angiography by cardiovascular interventionalists. In this article, we described the case of a 69\u2010year\u2010old female patient with recurrent chest discomfort for 1\u00a0month and recurrence 1\u00a0week ago, accompanied by emaciation, gastrointestinal discomfort, and low skin temperature at the extremities. After a series of tests, the patient was finally diagnosed with severe CAT and coexisting connective tissue disease. Accordingly, she was treated with conventional medications, and diet and lifestyle modifications. The symptoms of the patient resolved gradually after 1\u00a0year of follow\u2010up. Although there is no unanimous conclusion on the pathogenesis and clinical characteristics of CAT, this disease may provide a clue to the diagnosis of connective tissue disease, and warrants exploration through further research.<\/jats:p>","DOI":"10.1111\/anec.13052","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T14:13:57Z","timestamp":1676038437000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report of severe coronary artery tortuosity with coexisting connective tissue disease"],"prefix":"10.1111","volume":"28","author":[{"given":"Zao\u2010Xian","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Cardiac Rehabilitation Zhe Jiang Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiac Rehabilitation Zhe Jiang Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shang\u2010Ping","family":"Xin","sequence":"additional","affiliation":[{"name":"Department of Cardiac Rehabilitation Zhe Jiang Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong\u2010Fang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiac Rehabilitation Zhe Jiang Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8599-8030","authenticated-orcid":false,"given":"Xiao\u2010Ling","family":"Shou","sequence":"additional","affiliation":[{"name":"Department of Cardiac Rehabilitation Zhe Jiang Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000001593"},{"key":"e_1_2_11_3_1","first-page":"1189","article-title":"The angiographie definitions of the bypass angioplasty revasculariza\u2010tion investigation","volume":"3","author":"Alderman E. 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