{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T19:12:05Z","timestamp":1777576325576,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The prevalence of Holter\u2010based late potentials (H\u2010LPs) in cases of fatal cardiac events has increased. Although the noise level of H\u2010LP is higher than that of conventional real\u2010time late potential (LP) recording, a procedure to reduce the noise severity in H\u2010LP by increasing the averaging beats has not been investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 104 patients with post\u2010myocardial infarction (MI) and 86 control participants. Among the patients, 30 reported sustained ventricular tachycardia (VT), and the remaining 74 had unrecorded VT. H\u2010LPs were measured twice in all groups to evaluate the efficacy of increasing the averaging beats for H\u2010LPs. Thereafter, the average of LP was calculated at 250 (default setting), 300, 400, 500, 600, 700, and 800 beats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Across all three groups (MI\u2010VT group, MI non\u2010VT group, and control group), the noise levels significantly decreased in consonance with the increase in averaging beats. In the MI\u2010VT group, the H\u2010LP positive rate considerably increased with the increase in the averaging beats from 250 to 800 both at night and daytime. In the MI\u2010VT group, the LP parameters significantly deteriorated, which led to a positive judgment corresponding to the increment of the averaged night and day beats. The H\u2010LP positive rates were unchanged in the MI non\u2010VT and control groups, while the LP parameters remained consistent, despite the increased averaging beats in the MI non\u2010VT and control groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Increasing the calculated averaging beats in H\u2010LPs can improve the sensitivity of predicting fatal cardiac events in patients with MI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.13089","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T11:24:29Z","timestamp":1695122669000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Increasing averaging beats improves the test accuracy on Holter\u2010based late potentials in patients with myocardial infarction"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6838-1215","authenticated-orcid":false,"given":"Kenichi","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Harada","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motohiro","family":"Kimata","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"},{"name":"Department of Integrative Physiology and Bio\u2010Nano Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5469-0153","authenticated-orcid":false,"given":"Naoya","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinori","family":"Sekizawa","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Ono","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Obuchi","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadateru","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of General Medicine Nihon University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5021-1613","authenticated-orcid":false,"given":"Yuji","family":"Kasamaki","sequence":"additional","affiliation":[{"name":"Department of General Medicine Kanazawa Medical College Himi Municipal Hospital  Himi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of General Medicine National Defense Medical College  Tokorozawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2019.01.003"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.83.4.1481"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109149(90)90735\u2010j"},{"key":"e_1_2_13_5_1","first-page":"e61","article-title":"Low noise level unmasks late potentials on signal\u2010averaged electrocardiography","volume":"3","author":"Frances R. 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