{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:56:48Z","timestamp":1787795808279,"version":"build-2784847793"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>This systematic review of literature aimed to evaluate the safety and efficacy of dual\u2010chamber ICDs for LBBAP in patients with left bundle branch block (LBBB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Digital databases were searched systematically to identify studies reporting the left bundle branch area pacing (LBBAP) with implantable cardioverter defibrillator (ICD) placement in patients with LBBB. Detailed study and patient\u2010level baseline characteristics including the type of study, sample size, follow\u2010up, number of cases, age, gender, and baseline characteristics were abstracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a total of three studies, 34 patients were included in this review. There was a significant improvement reported in QRS duration in all studies. The mean QRS duration at baseline was 170\u2009\u00b1\u200917.4\u2009ms, whereas the follow\u2010up QRS duration at follow\u2010up was 121\u2009\u00b1\u200917.3\u2009ms. Two studies reported a significant improvement of 50% in LVEF from baseline. No lead\u2010related complications or arrhythmic events were recorded in any study. The findings of the systematic review suggest that dual\u2010chamber ICD for LBBAP is a promising intervention for patients with heart conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The procedure offers significant improvements in QRS duration and LVEF, and there were no lead\u2010related complications or arrhythmic events recorded in any of the studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.13098","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T07:05:05Z","timestamp":1700809505000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of dual\u2010chamber implantable cardioverter defibrillator for left bundle branch area pacing: A systematic review of literature"],"prefix":"10.1111","volume":"29","author":[{"given":"Muhammad","family":"Ahmad","sequence":"first","affiliation":[{"name":"Department of Medicine Al Saeed Medical Complex  Rahim Yar Khan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saffa","family":"Nadeem","sequence":"additional","affiliation":[{"name":"Department of Cardiology Multan Institute of Cardiology  Multan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafiz Ahmed","family":"Raza","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Social Security Hospital  Sheikuphura Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Wasey","family":"Hashmi","sequence":"additional","affiliation":[{"name":"Department of Medicine Shalamar Medical and Dental College  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawad","family":"Talat","sequence":"additional","affiliation":[{"name":"Department of Medicine King Edward Medical University  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Medicine Jinnah Sindh Medical University  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Muhammad Jawad","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Department of Medicine Ibn e Seena Hospital  Kabul Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4968-3909","authenticated-orcid":false,"given":"Amin","family":"Mehmoodi","sequence":"additional","affiliation":[{"name":"Department of Medicine Ibn e Seena Hospital  Kabul Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jahanzeb","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Research Cardiovascular Analytics Group  Islamabad 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Electrocardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anec.13098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T08:43:33Z","timestamp":1706604213000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/anec.13098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,23]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/anec.13098"],"URL":"https:\/\/doi.org\/10.1111\/anec.13098","archive":["Portico"],"relation":{},"ISSN":["1082-720X","1542-474X"],"issn-type":[{"value":"1082-720X","type":"print"},{"value":"1542-474X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,23]]},"assertion":[{"value":"2023-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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