{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:27:35Z","timestamp":1753878455006,"version":"3.41.2"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Acquired QT prolongation is frequent and leads to a higher mortality rate in critically ill patients. KardiaMobile 1L\u00ae (KM1L) is a portable, user\u2010friendly single lead, mobile alternative to conventional 12\u2010lead electrocardiogram (12\u2010L ECG) that could be more readily available, potentially facilitating more frequent QTc assessments in intensive care units (ICU); however, there is currently no evidence to validate this potential use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a prospective diagnostic test study comparing QT interval measurement using KM1L with conventional 12\u2010L ECG ordered for any reason in patients admitted to an ICU. We compared the mean difference using a paired <jats:italic>t<\/jats:italic>\u2010test, agreement using Bland\u2013Altman analysis, and Lin's concordance coefficient, numerical precision (proportion of QT measurements with &lt;10\u2009ms difference between KM1L and conventional 12\u2010L ECG), and clinical precision (concordance for adequate discrimination of prolonged QTc).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 114 patients (61.4% men, 60% cardiovascular etiology of hospitalization) with 131 12\u2010L ECG traces. We found no statistical difference between corrected QT measurements (427\u2009ms vs. 428\u2009ms, <jats:italic>p<\/jats:italic>\u2009=\u2009.308). Lin's concordance coefficient was 0.848 (95% CI 0.801\u20130.894, <jats:italic>p<\/jats:italic>\u2009=\u2009.001). Clinical precision was excellent in males and substantial in females (Kappa 0.837 and 0.781, respectively). Numerical precision was lower in patients with vasoactive drugs (\u221213.99\u2009ms), QT\u2010prolonging drugs (13.84\u2009ms), antiarrhythmic drugs (\u221212.87\u2009ms), and a heart rate (HR) difference of \u22655 beats per minute (bpm) between devices (\u221211.26\u2009ms).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study validates the clinical viability of KM1L, a single\u2010lead mobile ECG device, for identifying prolonged QT intervals in ICU patients. Caution is warranted in patients with certain medical conditions that may affect numerical precision.<\/jats:p><\/jats:sec>","DOI":"10.1111\/anec.13116","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T05:13:46Z","timestamp":1713330826000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of portable single\u2010lead electrocardiogram device as an alternative for QTc monitoring in critically ill patients"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4189-4317","authenticated-orcid":false,"given":"Martin","family":"Rebolledo\u2010Del\u00a0Toro","sequence":"first","affiliation":[{"name":"Division of Cardiology Hospital Universitario San Ignacio  Bogota Colombia"},{"name":"Department of Internal Medicine Pontificia Universidad Javeriana  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Beatriz","family":"Carvajalino\u2010Galeano","sequence":"additional","affiliation":[{"name":"Department of Medicine Pontificia Universidad Javeriana  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clarena","family":"Pinto\u2010Brito","sequence":"additional","affiliation":[{"name":"Department of Medicine Pontificia Universidad Javeriana  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar Mauricio","family":"Mu\u00f1oz\u2010Velandia","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Pontificia Universidad Javeriana  Bogota Colombia"},{"name":"Department of Internal Medicine Hospital Universitario San Ignacio  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1ngel Alberto","family":"Garc\u00eda\u2010Pe\u00f1a","sequence":"additional","affiliation":[{"name":"Division of Cardiology Hospital Universitario San Ignacio  Bogota Colombia"},{"name":"Department of Internal Medicine Pontificia Universidad Javeriana  Bogota Colombia"},{"name":"Department of Internal Medicine Hospital Universitario San Ignacio  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.5005\/JP\u2010JOURNALS\u201010071\u201024144"},{"key":"e_1_2_14_3_1","unstructured":"AliveCor. 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