{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:44:44Z","timestamp":1791798284682,"version":"4.3.4"},"reference-count":71,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Noninvasive Electrocardiol"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Ventricular Arrhythmias (VA) associated with Cardiomyopathy (CM) continues to be the major cause of death. However, a national longitudinal study examining mortality trends from these conditions is still lacking. This study assessed mortality trends due to these conditions among U.S. adults aged \u2265\u200925\u2009years from 1999 to 2024.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An observational analysis of U.S. mortalities due to VA in patients with CM (ICD\u201010 I47.2, I49.0 and I25.5, I42 respectively), was conducted using CDC WONDER. Adjusted Mortality Rates (AAMR) per 100,000 calculated and trends were assessed by calculating Average and Annual Percent Change (AAPC, APC), using joinpoint regression stratified by year, sex, race, and region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From 1999 to 2024, 81,204 VA with CM\u2010related deaths occurred with the overall AAMR declined from 2.54 in 1999 to 1.01 in 2024 (AAPC: \u22123.55%;\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.000001). AAMRs decreased from 1999 to 2007 (APC: \u22127.93), remained stable till 2022 (APC: \u22120.66), and dropped by 2024 (APC: \u22126.87). Men exhibited greater AAMRs (2.42) than women (0.68). Racially, the AAMRs were most pronounced in Non\u2010Hispanic (NH) Blacks (1.97), followed by NH Whites (1.42), whereas Hispanics and NH Others experienced similar AAMRs of 0.97. Geographically, Delaware and the Western regions experienced the highest rates of mortality (2.2 and 1.53, respectively). Urban areas had higher AAMRs than rural settings (1.45 vs. 1.4)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although VA\u2010CM mortality has declined over the past two decades, differences by race, sex, and geography remain, underscoring the need for targeted healthcare strategies<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anec.70234","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T08:45:38Z","timestamp":1791794738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Understanding the Mortality Trends in Patients With Ventricular Arrhythmias and Cardiomyopathy: A 25\u2010Year Retrospective Analysis From 1999\u20132024"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8750-5965","authenticated-orcid":false,"given":"Nosheen","family":"Pervaiz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Queen Elizabeth, Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-250X","authenticated-orcid":false,"given":"Hamza","family":"Naveed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Queen Elizabeth, Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8471-4261","authenticated-orcid":false,"given":"Muhammad Junaid","family":"Razzak","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1587-4320","authenticated-orcid":false,"given":"Shaheer Bin","family":"Shafiq","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0800-4830","authenticated-orcid":false,"given":"Muhammad","family":"Hasan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sawera","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dow Medical College Dow University of Health Sciences  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maham","family":"Abbasi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Capital Health Regional Medical Center  Trenton New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8208-0689","authenticated-orcid":false,"given":"Kamil Ahmad","family":"Kamil","sequence":"additional","affiliation":[{"name":"Chief, Department of Internal Medicine Nasrat Bashir Curative Hospital  Kandahar Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Ahmed","family":"Farhan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine McLaren Greater Lansing Hospital  Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.01.032"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.066605"},{"key":"e_1_2_13_4_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/978-3-319-44577-9_17","volume-title":"Congestive Heart Failure and Cardiac Transplantation: Clinical, Pathology, Imaging and Molecular Profiles","author":"Anand I. 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