{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:15:44Z","timestamp":1790806544182,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T00:00:00Z","timestamp":1359072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Urosepsis is the most common complication requiring hospital admission after transrectal biopsy of the prostate. This study aims to assess the local incidence and causative organisms of hospital admissions with urosepsis after transrectal ultrasound\u2010guided prostate (<jats:styled-content style=\"fixed-case\">TRUS<\/jats:styled-content>) biopsy. As morbidity is high, treatment must be commenced empirically prior to cultures. A review of bacterial antibiotic susceptibilities was undertaken to guide optimal treatment of post\u2010biopsy urosepsis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 1421 patients underwent <jats:styled-content style=\"fixed-case\">TRUS<\/jats:styled-content> biopsy in a single city over a 2\u2010year period. All patients received prophylactic antibiotics prior to the procedure. A retrospective review of a prospectively collated database was performed in all patients admitted to <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hristchurch Hospital, the only acute admitting hospital in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hristchurch, with infection within 30 days after biopsy. Hospital admission records were reviewed, including urine and blood culture results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty patients (2.8%) were admitted with infection after the biopsy, the majority occurring within the first week after procedure and four required intensive care unit (<jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>) admission (10%). The most common organism isolated on urine and blood cultures was <jats:italic>Escherichia coli<\/jats:italic>. Significant <jats:italic>E.\u2009coli<\/jats:italic> resistance was seen to fluoroquinolones, amoxicillin and trimethoprim.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Rates of infection after <jats:styled-content style=\"fixed-case\">TRUS<\/jats:styled-content> biopsy and antibiotic resistance are increasing internationally. Treatment for urosepsis should be aggressive as 10% of those patients admitted required <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content> admission. <jats:styled-content style=\"fixed-case\">TRUS<\/jats:styled-content> biopsy with ciprofloxacin prophylaxis led to infectious complications comparable with other international reports and appears to remain an appropriate prophylactic antibiotic of choice. Infections requiring hospital admission were all susceptible to a combination of ceftriaxone and gentamicin, and would be an effective initial antibiotic of choice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12073","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T12:27:52Z","timestamp":1359116872000},"page":"246-248","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Infection\u2010related hospital admissions after transrectal biopsy of the prostate"],"prefix":"10.1111","volume":"83","author":[{"given":"Andrew","family":"Sanders","sequence":"first","affiliation":[{"name":"Department of Urology Christchurch Hospital  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Buchan","sequence":"additional","affiliation":[{"name":"Urology Associates St George's Medical Centre  Christchurch New Zealand"},{"name":"Canterbury Urology Research Trust (CURT) St George's Medical Centre  Christchurch New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,1,25]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Ministry of Health NZ.Cancer: selected sites 2008 2009 and 2010.2011."},{"key":"e_1_2_6_3_1","first-page":"2735","volume-title":"Campbell\u2010Walsh Urology, 10th edn","author":"Trabulsi E","year":"2010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.11.043"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-005-0076-2"},{"key":"e_1_2_6_6_1","unstructured":"European Association of Urology.2012.Guidelines on prostate cancer."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.04.064"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2010.09416.x"},{"key":"e_1_2_6_9_1","unstructured":"Ministry of Health NZ.Cancer: historical summary 1948\u20132008.2011."},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10473.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.12.067"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000296290"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.12.058"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.02.065"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis194"}],"container-title":["ANZ Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fans.12073","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ans.12073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T03:58:45Z","timestamp":1697515125000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ans.12073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,25]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/ans.12073"],"URL":"https:\/\/doi.org\/10.1111\/ans.12073","archive":["Portico"],"relation":{},"ISSN":["1445-1433","1445-2197"],"issn-type":[{"value":"1445-1433","type":"print"},{"value":"1445-2197","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1,25]]},"assertion":[{"value":"2012-11-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-01-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}