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It is associated with a higher risk of developing post\u2010operative complications, prolongs hospital stay and confers a significant financial load on health\u2010care institutions. Literature outlining best\u2010practice management strategies for <jats:styled-content style=\"fixed-case\">PPOI<\/jats:styled-content> is nebulous. The aim of this text was to review the literature and provide concise evidence\u2010based recommendations for its management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A literature search through the Ovid <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">EMBASE<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>oogle <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cholar and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ochrane databases was performed from inception to <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>uly 2012 using a combination of keywords and <jats:styled-content style=\"fixed-case\">MeSH<\/jats:styled-content> terms. Review of the literature was followed by synthesis of concise recommendations for management accompanied by Strength of Recommendation Taxonomy (either A, B or C).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Recommendations for management include regular evaluation and correction of electrolytes (B); review of analgesic prescription with weaning of narcotics and substitution with regular paracetamol, regular non\u2010steroidal anti\u2010inflammatory drugs if not contraindicated, and regular or as\u2010required Tramadol (A); nasogastric decompression for those with nausea or vomiting as prominent features (C); isotonic dextrose\u2010saline crystalloid maintenance fluids administered within a restrictive regimen (B); balanced isotonic crystalloid replacement fluids containing supplemental potassium, in equivalent volume to losses (C); regular ambulation (C); parenteral nutrition if unable to tolerate an adequate oral intake for more than 7 days post\u2010operatively (A) and exclusion of precipitating pathology or alternate diagnoses if clinically suspected (C).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Recommendations have a variable and frequently inconsistent evidence base. Further research is required to validate many of the outlined recommendations and to investigate novel interventions that may be used to shorten duration of <jats:styled-content style=\"fixed-case\">PPOI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12102","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T17:41:06Z","timestamp":1361295666000},"page":"319-324","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":85,"title":["Management of prolonged post\u2010operative ileus: evidence\u2010based recommendations"],"prefix":"10.1111","volume":"83","author":[{"given":"Ryash","family":"Vather","sequence":"first","affiliation":[{"name":"Department of Surgery The University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Bissett","sequence":"additional","affiliation":[{"name":"Department of Surgery The University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.2.206"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181fcb83e"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-011-1339-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9491-2"},{"key":"e_1_2_6_6_1","first-page":"82","article-title":"Inpatient economic burden of postoperative ileus associated with abdominal surgery in the United States","volume":"32","author":"Goldstein JL","year":"2007","journal-title":"P&T"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000227765"},{"key":"e_1_2_6_8_1","first-page":"152","article-title":"Prevention of postoperative ileus","volume":"68","author":"Holte K","year":"2002","journal-title":"Minerva Anestesiol."},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0613-9"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.17.1.59"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/cgh.2003.50012"},{"key":"e_1_2_6_12_1","first-page":"228","volume-title":"Textbook of Medical Physiology","author":"Hall JE","year":"2006"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-3150.2004.00558.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/98.3.691"},{"key":"e_1_2_6_15_1","unstructured":"VatherR BissettIP.Risk Factors for the Development of Prolonged Postoperative Ileus following Elective Colorectal Surgery. 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