{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T14:44:45Z","timestamp":1775227485168,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T00:00:00Z","timestamp":1361232000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Early survival and quality of outcome after surgery for hypoplastic left heart syndrome (<jats:styled-content style=\"fixed-case\">HLHS<\/jats:styled-content>) are influenced by patient\u2010specific factors, the quality of surgery and perioperative care. Some skills are common to the care of other complex neonatal presentations but integrating this expertise is a key challenge for new programmes. We began offering surgery for <jats:styled-content style=\"fixed-case\">HLHS<\/jats:styled-content> from 2006 and provided a regional service from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2009 and report early outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospectively collected data for neonates with <jats:styled-content style=\"fixed-case\">HLHS<\/jats:styled-content> undergoing surgical palliation from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 2006 until <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>une 2011 were analysed. Standard definitions of high\u2010risk and standard\u2010risk presentations were utilized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty neonates underwent surgical palliation of <jats:styled-content style=\"fixed-case\">HLHS<\/jats:styled-content> with a modified Norwood procedure with an overall survival to stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> palliation of 80%. A total of 46.7% of our patients were categorized as high\u2010risk, mostly on the basis of low birth weight. Survival to stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> palliation was 100% in standard\u2010risk patients and 57.1% in the high\u2010risk group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Outcomes for this new programme are comparable to reported outcomes demonstrating the feasibility of integrating a new complex procedure within an existing multidisciplinary unit handling large volumes of other complex neonatal work. Excellent outcomes can be achieved in standard\u2010risk patients. Outcomes in the high\u2010risk group may be improved by alternative approaches and rigorous case selection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12103","type":"journal-article","created":{"date-parts":[[2013,2,19]],"date-time":"2013-02-19T17:41:09Z","timestamp":1361295669000},"page":"466-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early outcomes from a new regional programme for the surgical management of hypoplastic left heart syndrome"],"prefix":"10.1111","volume":"85","author":[{"given":"Yishay","family":"Orr","sequence":"first","affiliation":[{"name":"Heart Centre for Children, The Children's Hospital at Westmead, Sydney Children's Hospitals Network  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Leclair","sequence":"additional","affiliation":[{"name":"Heart Centre for Children, The Children's Hospital at Westmead, Sydney 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