{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:57:51Z","timestamp":1792180671326,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T00:00:00Z","timestamp":1372118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The BioLIFT<\/jats:styled-content> procedure involves placing a bioprosthetic graft in the intersphincteric space during the ligation of the intersphincteric fistula tract (LIFT<\/jats:styled-content>) procedure. Our study was aimed to describe our experience in the BioLIFT<\/jats:styled-content> procedure.<\/jats:p><\/jats:sec>Methods<\/jats:title>A review of all patients who underwent the BioLIFT<\/jats:styled-content> procedure for anal fistula from S<\/jats:styled-content>eptember 2011 to A<\/jats:styled-content>ugust 2012 was performed. Endoanal ultrasonography and manometry tests were performed in all patients.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirteen patients with 16 fistulas underwent the BioLIFT<\/jats:styled-content> procedure. All of them had at least a seton inserted previously and the median interval to the BioLIFT<\/jats:styled-content> procedure was 20 (range, 10\u201341) weeks. Four patients failed a prior LIFT<\/jats:styled-content> procedure. More than half of the fistulas (56.3%) had anterior internal openings and there was a female preponderance (n<\/jats:italic> = 7, 53.8%). Over a median follow up of 26 (12\u201351) weeks, 11 (68.8%) fistulas had healed. The median interval between the BioLIFT<\/jats:styled-content> procedure to the diagnosis of failure was 3 (2\u20137) weeks. All five failures had only isolated discharges at the intersphincteric wounds. Two had already undergone successful lay\u2010open fistulotomy, giving a secondary success rate of 81.3%. The remaining three patients are on review. No patient developed incontinent symptoms following the BioLIFT<\/jats:styled-content> procedure and there were no significant differences between the pre\u2010procedural or post\u2010procedural maximal resting and squeeze anal manometric pressures.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The BioLIFT<\/jats:styled-content> procedure can achieve a primary success rate of 68.8%. When coupled with a simple lay\u2010open fistulotomy for the subsequent intersphincteric fistula, the success rate in eradicating the fistula rose to 81.3%.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12242","type":"journal-article","created":{"date-parts":[[2013,6,25]],"date-time":"2013-06-25T05:18:51Z","timestamp":1372137531000},"page":"280-283","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Early experience of reinforcing the ligation of the intersphincteric fistula tract procedure with a bioprosthetic graft (BioLIFT<\/scp>) for anal fistula"],"prefix":"10.1111","volume":"84","author":[{"given":"Ker\u2010Kan","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery Royal Prince Alfred Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery Royal Prince Alfred Hospital Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,25]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"581","article-title":"Total anal sphincter saving technique for fistula\u2010in\u2010ano: the ligation of intersphincteric fistula tract","volume":"90","author":"Rojanasakul A","year":"2007","journal-title":"J. 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