{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:59:54Z","timestamp":1787626794981,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T00:00:00Z","timestamp":1374796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2015,4]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The benefits of central compartment dissection (CCD<\/jats:styled-content>) in papillary thyroid carcinoma (PTC<\/jats:styled-content>) are still debatable and should be weighed against its potential risks. We aim to compare the complication rates in total thyroidectomy with and without CCD<\/jats:styled-content> for patients with PTC<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>This is a retrospective study on prospectively collected data from our cancer registry over a 15\u2010year period. Patients with pathologically proven PTC treated with total thyroidectomy alone or with CCD<\/jats:styled-content> were included. CCD<\/jats:styled-content> was performed at the operating surgeon's discretion. A total of 105 patients were included and divided into two groups for analysis: group A \u2013 total thyroidectomy alone (51 patients, 49%) and group B \u2013 total thyroidectomy with CCD<\/jats:styled-content> (54 patients, 51%). The operative complications between the two groups were then evaluated.<\/jats:p><\/jats:sec>Results<\/jats:title>Overall, 6.9% and 0.98% patients had transient and permanent recurrent laryngeal nerve palsies, respectively. About 19.0% and 2.9% patients had transient and permanent hypoparathyroidism, respectively and 27.6% patients had parathyroid glands found to be included in the resected specimen. Complication rates in terms of transient or permanent recurrent laryngeal nerve palsy or hypoparathyroidism did not differ significantly between groups A and B. Within group B, 41 patients had unilateral CCD<\/jats:styled-content> and 12 had bilateral CCD<\/jats:styled-content>. Transient hypoparathyroidism was more frequent in bilateral CCD<\/jats:styled-content> (50% versus 12.2%, P<\/jats:italic> = 0.01).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Total thyroidectomy with prophylactic unilateral CCD<\/jats:styled-content> is a safe procedure for PTC<\/jats:styled-content> without added complication rates compared with total thyroidectomy alone. It is recommended for patients with PTC<\/jats:styled-content> and clinically negative neck lymph nodes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12343","type":"journal-article","created":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T12:20:33Z","timestamp":1374841233000},"page":"274-278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Complication rates of central compartment dissection in papillary thyroid cancer"],"prefix":"10.1111","volume":"85","author":[{"given":"Wai\u2010Yin Wilson","family":"Kwan","sequence":"first","affiliation":[{"name":"Division of Head and Neck Surgery Department of Surgery United Christian Hospital Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u2010Lin","family":"Chow","sequence":"additional","affiliation":[{"name":"Division of Head and Neck Surgery Department of Surgery United Christian Hospital Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi\u2010Yee","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Head and Neck Surgery Department of Surgery United Christian Hospital Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siu\u2010Ho","family":"Lam","sequence":"additional","affiliation":[{"name":"Division of Head and Neck Surgery Department of Surgery United Christian Hospital Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,26]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Hospital Authority.Hong Kong Cancer Registry web site. 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