{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T02:49:56Z","timestamp":1776912596561,"version":"3.51.2"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,9,16]],"date-time":"2013-09-16T00:00:00Z","timestamp":1379289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Colorectal cancer is common and primarily a disease of older people. Colorectal cancer in patients aged 25 years and under is infrequent and may represent a unique subgroup of patients. This study aimed to describe the population of young people in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand diagnosed with colorectal cancer, their tumour characteristics, management and outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective clinical study was conducted via review of medical records for all patients 25 years of age and under, diagnosed with colorectal adenocarcinoma in <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand between 1 <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1997 and 31 <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2007.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty patients with colorectal adenocarcinoma were identified from the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>egistry. Seven had a positive family history of colorectal cancer, while eight had predisposing factors (hereditary nonpolyposis colorectal cancer, familial adenomatous polyposis, ulcerative colitis, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>rohn's disease, regional enteritis). The most common presenting symptoms were abdominal pain and weight loss. Twenty\u2010eight cases presented acutely. Eighteen presented with stage IV disease at diagnosis. Eighteen were referred to a genetics service. Five\u2010year overall survival was 49%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Those aged 25 years and under that develop colorectal cancer tend to present acutely and move through the secondary care pathway swiftly, being diagnosed at a more advanced stage, and have a poorer prognosis than their adult counterparts. Familial cancers form a more significant component of youth colorectal cancers compared to the older population and input from genetic service should be considered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12380","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T14:23:24Z","timestamp":1381242204000},"page":"371-375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Colorectal adenocarcinoma cancer in <scp>N<\/scp>ew <scp>Z<\/scp>ealand in those under 25 years of age (1997\u20132007)"],"prefix":"10.1111","volume":"84","author":[{"given":"Michael","family":"Plunkett","sequence":"first","affiliation":[{"name":"Discipline of Oncology, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Murray","sequence":"additional","affiliation":[{"name":"Discipline of Oncology, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Frizelle","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Department of Surgery Christchurch Hospital and University of Otago  Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lochie","family":"Teague","sequence":"additional","affiliation":[{"name":"Department of Haematology Starship Children's Hospital  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Hinder","sequence":"additional","affiliation":[{"name":"Discipline of Oncology, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Findlay","sequence":"additional","affiliation":[{"name":"Discipline of Oncology, Faculty of Medical and Health Sciences University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,16]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Ministry of Health.Cancer: New Registrations and Deaths 2009.2012. 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