{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:53:45Z","timestamp":1778637225358,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T00:00:00Z","timestamp":1397606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Local resection (<jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>) is a potentially effective alternative to pancreaticoduodenectomy for treatment of ampullary cancer, but the prognostic factors remain undefined. The purpose of this study was to identify the prognostic factors for ampullary cancer patients who had undergone <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed the clinical, pathological data and surgical approach of 34 ampullary cancer patients who had undergone <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> during 1996\u20132009 at <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>eople's <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>iberation <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>rmy <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>eneral <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital. Prognostic factors for survival and recurrence were analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 1\u2010, 3\u2010 and 5\u2010year survival rates of the patients were 97.1, 69.5 and 53.7%, respectively. The gender, age, preoperative bilirubin levels, <jats:styled-content style=\"fixed-case\">CA<\/jats:styled-content>19\u20109 levels and preoperative biopsy did not correlate with the survival rates. The survival rates of patient with <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>1 and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>2 tumours were superior to that of patients with <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>3 tumours (<jats:italic>P<\/jats:italic> = 0.000). Tumour size, surgical margin status and the extent of differentiation had no effect on survival rates (<jats:italic>P<\/jats:italic> = 0.464, <jats:italic>P<\/jats:italic> = 0.601 and <jats:italic>P<\/jats:italic> = 0.121, respectively). The survival rate of patients who had extraduodenal <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> (12 cases) was superior to that of patients who had transduodenal <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> (22 cases) (<jats:italic>P<\/jats:italic> = 0.026). Tumour recurrence occurred in 14 (41.2%) patients. Tumour infiltration (<jats:italic>P<\/jats:italic> = 0.014) correlated with the recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The degree of tumour infiltration is the pathological factor that most affects the survival of ampullary cancer patients who undergo <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>. Extraduodenal <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content> is a promising surgical procedure, the efficacy of which is superior to that of transduodenal <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>. The depth of tumour invasion correlated with the recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12600","type":"journal-article","created":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T07:32:35Z","timestamp":1397633555000},"page":"567-571","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prognostic factors for survival of patients with ampullary carcinoma after local resection"],"prefix":"10.1111","volume":"85","author":[{"given":"Xiangqian","family":"Zhao","sequence":"first","affiliation":[{"name":"Hospital and Institute of Hepatobiliary Surgery Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahong","family":"Dong","sequence":"additional","affiliation":[{"name":"Hospital and Institute of Hepatobiliary Surgery Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqiang","family":"Huang","sequence":"additional","affiliation":[{"name":"Hospital and Institute of Hepatobiliary Surgery Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenzhi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Hospital and Institute of Hepatobiliary Surgery Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Jiang","sequence":"additional","affiliation":[{"name":"Hospital and Institute of Hepatobiliary Surgery Chinese PLA General Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0883-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpa.0000220864.80034.63"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1622.2001.02185.x"},{"key":"e_1_2_5_5_1","first-page":"23","article-title":"Prognostic analysis of carcinoma of the ampulla of Vater: pancreaticoduodenectomy versus local resection","volume":"16","author":"Feng J","year":"2012","journal-title":"Hippokratia."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.12047"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/145749691110000205"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0444-1"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/000313481107700322"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-7985-8"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000167853.04171.bb"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e318258fda8"},{"key":"e_1_2_5_13_1","first-page":"319","article-title":"Transduodenal resection of ampullary tumors","volume":"137","author":"Distler M","year":"2012","journal-title":"Zentralbl. 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