{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:58:36Z","timestamp":1790179116434,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Correct diagnosis of the variants of papillary thyroid carcinoma (<jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content>) is important because these variants differ in clinical course. The Warthin\u2010like variant (<jats:styled-content style=\"fixed-case\">WLV<\/jats:styled-content>) is relatively uncommon and is recognized as not different from conventional <jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content>. We therefore assessed the clinicopathological features of patients with <jats:styled-content style=\"fixed-case\">WLV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content> who were diagnosed and treated at our institution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of the 8179 patients treated for <jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content> at the Thyroid Cancer Center, Gangnam Severance Hospital, Yonsei University College of Medicine, between January 2007 and December 2012, 16 patients (0.2%) were pathologically diagnosed with <jats:styled-content style=\"fixed-case\">WLV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content>. Their clinicopathological features and post\u2010operative follow\u2010up for local recurrence and distant metastasis were retrospectively investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>Mean patient age was 44.9 years (range: 23\u201361 years), with seven (44%) being younger than 45 years. Only one of the 16 patients was male (6%). Mean tumour size was 8.9 mm (range: 3\u201322 mm). Extrathyroidal extension was observed in seven patients (44%), associated thyroiditis in 11 (69%) and lymph node metastasis in six (38%). The mean follow\u2010up period was 37 months (range: 13\u201378 months), during which none of the 16 patients experienced recurrence or metastasis. Fifteen patients (94%) had <jats:styled-content style=\"fixed-case\">MACIS<\/jats:styled-content> score &lt;6, with the remaining patient having a <jats:styled-content style=\"fixed-case\">MACIS<\/jats:styled-content> score of 6.33.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">WLV<\/jats:styled-content> of <jats:styled-content style=\"fixed-case\">PTC<\/jats:styled-content> is rare, with favourable prognosis. Nevertheless, it is important to determine the histopathological features of these tumours.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12725","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T05:06:05Z","timestamp":1404277565000},"page":"492-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Warthin\u2010like variant of papillary thyroid carcinoma: single institution experience"],"prefix":"10.1111","volume":"86","author":[{"given":"Hak Hoon","family":"Jun","sequence":"first","affiliation":[{"name":"CHA Bundang Medical Center, Department of Surgery CHA University  Seongnam\u2010si Gyeonggi\u2010do Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok\u2010Mo","family":"Kim","sequence":"additional","affiliation":[{"name":"Thyroid Cancer Center, Department of Surgery, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon Won","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pathology, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Sang","family":"Lee","sequence":"additional","affiliation":[{"name":"Thyroid Cancer Center, Department of Surgery, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang\u2010Seok","family":"Chang","sequence":"additional","affiliation":[{"name":"Thyroid Cancer Center, Department of Surgery, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheong Soo","family":"Park","sequence":"additional","affiliation":[{"name":"Thyroid Cancer Center, Department of Surgery, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00353761"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.4.7407"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-2129-x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21494"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1385\/EP:16:4:323"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.5858\/2000-124-1192-WLPCOT","article-title":"Warthin\u2010like papillary carcinoma of the thyroid","volume":"124","author":"Baloch ZW","year":"2000","journal-title":"Arch. 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