{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:26:00Z","timestamp":1792797960307,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T00:00:00Z","timestamp":1409616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Gillies McIndoe Research Institute","id":[{"id":"https:\/\/ror.org\/000neg726","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Ethanol sclerotherapy (\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      ) is the preferred treatment for venous malformation (\n                      <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content>\n                      ) with surgery playing an adjunctive role. Results of\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      , however, are not well documented in the literature.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content>\n                      patients were identified from our vascular anomalies database from 1996 to 2011. After treatment completion, patients completed questionnaires evaluating symptoms and their severity and effect on appearance, function and overall quality of life (\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      ), before and &gt;6 months after treatment, using visual analogue scales of 0\u201310. Patients rated their overall satisfaction with\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      using a scale of 0\u201310.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010four (23.9%) of the 226\n                      <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content>\n                      patients underwent a total of 90\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      sessions (average 1.7 sessions per patient). Complications occurred in 12 (22.2%) patients in 12 (13.3%)\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      sessions. Minor complications occurred in nine (16.7%) patients including transient paraesthesia (\n                      <jats:italic>n<\/jats:italic>\n                      = 3), transient weakness of facial nerve branch(es) (\n                      <jats:italic>n<\/jats:italic>\n                      = 3), skin blistering (\n                      <jats:italic>n<\/jats:italic>\n                      = 2) and spontaneously healing ulceration (\n                      <jats:italic>n<\/jats:italic>\n                      = 1). Major complications occurred in three (5.6%) patients in three (3.3%)\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      sessions including skin necrosis (\n                      <jats:italic>n<\/jats:italic>\n                      = 1),\n                      <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>\n                      orner's syndrome (\n                      <jats:italic>n<\/jats:italic>\n                      = 1) and finger paraesthesia with joint stiffness (\n                      <jats:italic>n<\/jats:italic>\n                      = 1).\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      improved the severity of background pain, episodic pain, contour deformity and skin discoloration in 86.0%, 72.4%, 83.0% and 72.2% of patients respectively. It reduced the effect of\n                      <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content>\n                      on appearance, function and overall\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      in 69.8%, 73.0% and 64.3% of patients. Mean treatment satisfaction was 7.9 (range, 0\u201310).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">ES<\/jats:styled-content>\n                      reduces pain, contour deformity and skin discoloration, and improves appearance, function and\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      . Our complication rates are consistent with the literature.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ans.12833","type":"journal-article","created":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T22:39:38Z","timestamp":1409697578000},"page":"790-795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Ethanol sclerotherapy for venous malformation"],"prefix":"10.1111","volume":"86","author":[{"given":"Frederica","family":"Steiner","sequence":"first","affiliation":[{"name":"Gillies McIndoe Research Institute  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"FitzJohn","sequence":"additional","affiliation":[{"name":"Centre for the Study &amp; Treatment of Vascular Birthmarks Wellington Regional Plastic Maxillofacial &amp; Burns Unit Hutt Hospital  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swee T.","family":"Tan","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute  Wellington New Zealand"},{"name":"Centre for the Study &amp; Treatment of Vascular Birthmarks Wellington Regional Plastic Maxillofacial &amp; Burns Unit Hutt Hospital  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,2]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"375","article-title":"Vascular tumors and vascular malformations","volume":"13","author":"Enjolras O","year":"1997","journal-title":"Adv. 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