{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:52:35Z","timestamp":1773327155521,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T00:00:00Z","timestamp":1415059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ANZ Journal of Surgery"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To study the magnitude of radiation cystitis following radiation therapy for carcinoma cervix, and propose an algorithm to decide on early diversion, with or without vesicovaginostomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women who developed radiation cystitis following radiotherapy for carcinoma cervix from <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary 1998 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2011 were included in this retrospective study. Electronic hospital records were analysed to document the presence of radiation cystitis. All women who developed evidence of radiation\u2010induced cystitis, according to the common toxicity and <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>adiation <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>herapy <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ncology <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>roup criteria, were included in the study. We looked at transfusion requirements, number of hospital admissions, quality of life and cost involved. <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hi\u2010square tests were done where applicable. <jats:styled-content style=\"fixed-case\">SPSS<\/jats:styled-content> version 16 was used for analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 902 patients who received radiation for carcinoma cervix in the 13\u2010year period, 62 (6.87%) developed grade 3\/4 cystitis. Twenty\u2010eight of them underwent ileal conduit diversion, with 18 undergoing concomitant vesicovaginostomy. When compared with the patients who did not have diversion, the transfusion requirements, number of hospital admissions and quality of life had a statistically significant difference. Cost analysis of early diversion too showed a marginal benefit with early diversion. The limitation of the study was that it was retrospective in nature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In radiation cystitis, multiple hospital admissions and consequential increase in cost is the norm. In severe disease, early diversion is a prudent, cost\u2010effective approach with good quality of life and early return to normal activity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ans.12898","type":"journal-article","created":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T11:17:44Z","timestamp":1415099864000},"page":"770-773","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early urinary diversion with ileal conduit and vesicovaginostomy in the treatment of radiation cystitis due to carcinoma cervix: a study from a tertiary care hospital in <scp>S<\/scp>outh <scp>I<\/scp>ndia"],"prefix":"10.1111","volume":"85","author":[{"given":"John Samuel","family":"Banerji","sequence":"first","affiliation":[{"name":"Department of Urology Christian Medical College  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antony","family":"Devasia","sequence":"additional","affiliation":[{"name":"Department of Urology Christian Medical College  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin Sudhakar","family":"Kekre","sequence":"additional","affiliation":[{"name":"Department of Urology Christian Medical College  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ninan","family":"Chacko","sequence":"additional","affiliation":[{"name":"Department of Urology Christian Medical College  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,11,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2010.02.007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.06.034"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)00431-J"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000049760"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2005.06.013"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)41016-0"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(90)80247-K"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06293.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62770-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.1996.05615.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800530319"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0022-5347(17)60646-3","article-title":"The occurrence of empyema cystis; management of the bladder to be defunctionalized","volume":"108","author":"Dretler SP","year":"1972","journal-title":"J. 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